Sökning: "copy-number"

Visar resultat 1 - 5 av 22 uppsatser innehållade ordet copy-number.

1. 1. Skillnad i pilE genkopieantal och genuttryck mellan Neisseria meningitidis vid invasiv sjukdom eller bärarskap

   Kandidat-uppsats, Örebro universitet/Institutionen för hälsovetenskaper

   Författare :Sara Al-Haseny; [2023]
   Nyckelord :Neisseria meningitidis; invasive disease; carriage; pilE; digital droplet PCR; Neisseria meningitidis; invasiv sjukdom; bärarskap; pilE; digital droplet PCR;

   Sammanfattning : Neisseria meningitidis är en bakterie som kan leda till invasiv sjukdom eller endast orsaka bärarskap i nasopharynx. Bakterien delas in i olika serogrupper och klonala komplex. LÄS MER

3. 2. Detecting structural variants in the DNA of the inbred Scandinavian wolf

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Lars Huson; [2023]
   Nyckelord :animal; animal population; bioinformatics; biological sciences; biology; Canis lupus; CNV; conservation genetics; conservation genomics; copy-number variation; DNA; endangered population; endangered species; evolution; evolutionary biology; extinction; genetic diversity; genetics; genetic variation; genomes; genomics; grey wolf; inbreeding; inbreeding depression; indel; mutation; pedigree; population genetics; population genomics; Scandinavia; smoove; snakemake; structural variant; SV; wolf; wolves;

   Sammanfattning : Only 40 years ago, just three individuals made the journey from Finland/Russia to found the current wolf population in the southwest of Sweden. This population, that to this date descends from less than 10 founders, has a substantial increased extinction risk due to inbreeding. LÄS MER

4. 3. The relative contribution of CNVs and SNPs to local adaptation in Norway spruce (Picea abies)

   Master-uppsats, Uppsala universitet/Växtekologi och evolution; Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Yuxuan Niu; [2022]
   Nyckelord :CNVs; SNPs; Norway spruce; local adaptation;

   Sammanfattning : In the current environment of severe climate change, studying the adaptability of Norway spruce to the environment, that is, local adaptation is of great significance for helping to protect forest tree species and genetic breeding. As a structural variation, copy number variations (CNVs) have been proved to play an important role in shaping population structure and local adaptation in marine species, going beyond traditional studies focusing only on SNPs. LÄS MER

5. 4. Implementing ExomeDepth with a variant filter as a CNV-calling tool for germline clinical diagnostic testing

   Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

   Författare :Alice Krysén; [2022]
   Nyckelord :;

   Sammanfattning : Copy number variations (CNVs) cover approximately 4.9 - 9.5% of the human genome. CNVs are involved in both the development of disease and evolutionary adaptions. LÄS MER

7. 5. Production of 5-ketogluconic acid using recombinant strains of Gluconobacter oxydans

   Master-uppsats, Lunds universitet/Bioteknik (CI); Lunds universitet/Bioteknik (master)

   Författare :Aakash Reddy Murugadasan; [2022]
   Nyckelord :Gluconobacter oxydans; Escherichia coli; 5-Keto-D-gluconic acid; Alcohol dehydrogenase; Biotechnology; Biology and Life Sciences;

   Sammanfattning : 5-Keto-D-gluconic acid (5-KGA) is a valuable compound that has a wide range of applications in the chemical and food industries and is commonly used as a precursor for manufacturing tartaric acid (TA). Industrial production of 5-KGA through chemical approaches was practiced in the early 1920’s and was dropped immediately due to several drawbacks because of its complicated process that resulted in lower 5-KGA yield and higher accumulation of impure gluconic acid. LÄS MER