Sökning: "cytarabine"

Hittade 3 uppsatser innehållade ordet cytarabine.

  1. 1. Combination of Antimetabolites with Chemotherapy as a Novel Treatment Option in High-risk Neuroblastoma

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Maja Lundström; [2022]
    Nyckelord :cell cycle arrest; chemotherapy resistance; combination therapy; cytarabine; doxorubicin; gemcitabine;

    Sammanfattning : 20 svenska barn diagnostiseras årligen med barntumören neuroblastom (NB). Läkemedelsresistens och intratumoral heterogenitet försvårar behandlingen och 50-60% av hög-risk NB-patienter drabbas av återfall. Subpopulationer av resistenta celler har identifierats i hög-risk NB-cellinjer, vilket belyser behovet av nya behandlingsalternativ. LÄS MER

  3. 2. Treatment of a mantle cell lymphoma cell line with cannabinoids and cytostatics : - effects on DNA synthesis and ceramide metabolism

    Master-uppsats, Akademin för hållbar samhälls- och teknikutveckling; Institutionen för biologi och kemiteknik

    Författare :Ablahad Chabo; [2009]
    Nyckelord :cancer; mantle cell lymphoma; cannabinoids; cytostatics; ceramide;

    Sammanfattning : Mantle cell lymphoma (MCL) is an aggressive B-cell malignancy with bad prognosis, which predominates in males with advanced age. However, studies of the endocannabinoid system and how it affects tumour behaviour provides the basis for designing innovative therapeutic strategies that could open new opportunities for treatment of patient with MCL. LÄS MER

  4. 3. Do the new signal transduction modulators have activity in vitro in tumor cells from ovarian carcinoma and lymphoma?

    Kandidat-uppsats, Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Desiré Lundin; [2005]
    Nyckelord :Anticancer drug development; ovarian carcinoma; lymphoma; FMCA; cytotoxic drugs; in vitro assay;

    Sammanfattning : During the last decades, chemotherapy with cytotoxic drugs has played a significant role in cancer therapy. It’s important to develop new anticancer drugs, and drug sensitivity testing in vitro can be used to find the right diagnosis for the newly developed substances. LÄS MER