Sökning: "deadenylation"

Hittade 1 uppsats innehållade ordet deadenylation.

  1. 1. Determining the oligomeric structure of PARN

    Master-uppsats, Institutionen för cell- och molekylärbiologi

    Författare :Mikael Nissbeck; [2012]
    Nyckelord :Poly A -specific ribonuclease PARN ; deadenylation; mRNA metabolism; cap stimulation; oligomerization;

    Sammanfattning : Poly(A)-specific ribonuclease (PARN) is a deadenylase that degrades the poly(A) tail of eukaryotic mRNA. PARN also interacts with the 5’-cap structure of the mRNA. The binding of the cap structure enhances the deadenylation rate. PARN has previously been described as a dimer. LÄS MER