Sökning: "degradants"
Hittade 2 uppsatser innehållade ordet degradants.
1. Development and validation of an ultrahigh-performance liquid chromatography method for identity, assay and impurity testing of nicotine and preservatives in nicotine nasal spray
M1-uppsats, Lunds universitet/Centrum för analys och syntesSammanfattning : The topic of this study is to develop and validate an analysis method of nicotine nasal spray produced at McNeil AB. When developing the analysis method, several parameters were determined in advance to make the method more similar to other analysis methods at the company, making it more practical. LÄS MER
2. Evaluation of a UPLC-MS method using 18O-labelled water for the identification of hydrolytic degradants of drug substances
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för analytisk farmaceutisk kemiSammanfattning : In this master’s thesis the hydrolytic degradation in 18O-water solutions of six drug substances has been studied. The aim was to develop a mass spectrometric method for easier identification of degradants, since hydrolysis in 18O-water will generate degradants with higher mass compared with hydrolysis in regular water. LÄS MER