Sökning: "disease modeling"

Visar resultat 1 - 5 av 24 uppsatser innehållade orden disease modeling.

  1. 1. Modelling conversion of adult skin cells to neurons

    Master-uppsats, Lunds universitet/Institutionen för astronomi och teoretisk fysik; Lunds universitet/Beräkningsbiologi och biologisk fysik

    Författare :Viktor Drugge; [2018]
    Nyckelord :Human adult fibroblast; Neuron; Neural conversion; Transdifferentiation; Direct reprogramming; Direct lineage conversion; Simulation; Regulatory gene network; Gene network topology; Gene circuit; Gene dynamics; Physics and Astronomy;

    Sammanfattning : Scientists are now able to directly convert one somatic cell type into another using a procedure known as direct lineage reprogramming or transdifferentiation. In this procedure, transcription factors which are important for initiating a rewriting of the gene expressions are introduced in the cell. LÄS MER

  2. 2. Bayesian Parameterization in the spread of Diseases

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för beräkningsvetenskap

    Författare :Robin Eriksson; [2017]
    Nyckelord :Bayesian Inference; likelihood-free; Markov chain Monte Carlo; Approximate Bayesian Computations; Synthetic likelihood; Epidemiology; disease modeling;

    Sammanfattning : Mathematical and computational epidemiological models are important tools in efforts to combat the spread of infectious diseases. The models can be used to predict further progression of an epidemic and for assessing potential countermeasures to control disease spread. LÄS MER

  3. 3. Segmentation of high frequency 3D ultrasound images for skin disease characterization

    Master-uppsats, KTH/Teknisk informationsvetenskap

    Författare :Adrien Anxionnat; [2017]
    Nyckelord :level-set segmentation; active contours; optimization; statistical modeling; Blitz ;

    Sammanfattning : This work is rooted in a need for dermatologists to explore skin characteristicsin depth. The inuence of skin disease such as acne in dermal tissues is stilla complex task to assess. Among the possibilities, high frequency ultrasoundimaging is a paradigm shift to probe and characterizes upper and deep dermis. LÄS MER

  4. 4. Adaptation of existing cardiovascular simulation model to cardiac pumping physiology

    Master-uppsats, Lunds universitet/Avdelningen för Biomedicinsk teknik

    Författare :Emma Törner; [2017]
    Nyckelord :The CircAdapt model; biomedical modeling; cardiovascular; cardiac pumping; simulation; Technology and Engineering;

    Sammanfattning : Cardiovascular diseases, affecting the heart and blood vessels, are the most common cause of death globally. However, the risk of suffering from a cardiovascular disease could decrease significantly as research improve treatment and identification of symptoms. LÄS MER

  5. 5. Evaluation of the Cost-Effectiveness of Novel Tests in the Screening and Diagnostic Phases of Prostate Cancer Compared to Current Practice

    Master-uppsats, Lunds universitet/Avdelningen för Biomedicinsk teknik

    Författare :Ebba Palenius; Elin Bonnevier; [2017]
    Nyckelord :Prostate Cancer; Cost-Effectiveness; Screening; Clinical Utility; Markov modeling; Biopsy; TreeAge; Technology and Engineering;

    Sammanfattning : Introduction: There are major limitations in the current methods for screening and diagnosis of prostate cancer. In this project, the implementation of new tests has been researched. The assessed tests in the screening phase are the 4Kscore, Prostate Health Index (PHI), Magnetic Resonance Imaging (MRI) and Prostarix. LÄS MER