Sökning: "dried blood spots"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden dried blood spots.

1. 1. Genetics of complement proteins among Swedish newborns

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Xinyao Sun; [2022]
   Nyckelord :genetics; complement protein; newborns; haplotype analysis;

   Sammanfattning : Complement proteins play an important role in the body's immune processes and involve in the pathology of many diseases in human, such as major depressive disorder and schizophrenia. Understanding the genetics of those proteins is an important step toward unraveling their effects on psychiatric disorders. LÄS MER

3. 2. Assessing the efficacy of artemisinin-based combination therapies (ACTs) against Plasmodium malariae and Plasmodium ovale infections with low parasite densities: overcoming challenges during molecular analyses

   Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

   Författare :Ioanna Broumou; [2020]
   Nyckelord :Malaria; Plasmodium malariae; Plasmodium ovale; low density infections; PCR detection;

   Sammanfattning : Background: Malaria is a major public health issue. Artemisinin-based combination therapies are the WHO recommended treatment for uncomplicated malaria. Plasmodium malariae and Plasmodium ovale infections are considered underestimated and the effectiveness of artemisinin-based combination treatments against them is poorly documented. LÄS MER

4. 3. Microfluidic blood fractionation and lysis towards analysis of cytokine levels in red blood cells

   Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

   Författare :Laura Barrett; [2019]
   Nyckelord :Microfluidics; Capillary action; Blood; Fractionation; Cytokine; Interleukin 3;

   Sammanfattning : In the process of blood analysis, for biomarker detection, blood plasma or serumis analyzed, while Red blood cells (RBCs) are usually considered waste. A recentstudy has found that cytokine concentrations in RBC lysate are on average 12-fold higher than in plasma. LÄS MER

5. 4. Design of an LC-MS/MS method for measuring concentrations of Cyclosporine A and Tacrolimus from dried blood spots

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för analytisk farmaceutisk kemi

   Författare :Anna Hansson; [2015]
   Nyckelord :LC-MS MS; Dried blood spots; Immunosuppressive drugs;

   Sammanfattning : Patients that have undergone organ transplantation are life-long treated with immunosuppressant drugs and these have to be monitored regularly to get the desired effect of suppressing the immune system. To monitor the drug concentration normally a venous blood sample is collected at a clinic but the use of dried blood spots (DBS) as a matrix for drug monitoring for immunosuppressant drugs will make home sampling possible for this patient group. LÄS MER

7. 5. Development and evaluation of procedures and reagents for extraction of proteins from dried blood spots for analysis using Proseek

   Master-uppsats, Institutionen för biologisk grundutbildning

   Författare :Johan Björkesten; [2014]
   Nyckelord :DBS; dried blood spots; PEA; Proseek; Proseek Multiplex; qPCR; Protein detection; Olink;

   Sammanfattning : A method for extraction of proteins from dried blood spots (DBS) for analysis using Proseek is developed and evaluated. DBS, as sample format, possesses a number of desirable advantages over for example plasma samples. These advantages include for example minimal patient invasiveness, sampling simplicity and non regulated sample transportation. LÄS MER