Sökning: "dual distribution"

Visar resultat 1 - 5 av 45 uppsatser innehållade orden dual distribution.

1. 1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk kemi

   Författare :Maryam Dost; [2024]
   Nyckelord :Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

   Sammanfattning : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. LÄS MER

3. 2. Effektivitet och säkerhet av sakubitril/valsartan vid farmakologisk behandling av hypertoni : En litteraturöversikt om effektiviteten och säkerhetsprofilen av angiotensinreceptor-neprilysinhämmare (ARNI) vid hypertonibehandling

   Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

   Författare :Blerina Isufi; [2023]
   Nyckelord :Hypertension; sacubitril valsartan; LCZ696; ARNI; Hypertoni; sakubitril valsartan; LCZ696; ARNI;

   Sammanfattning : Introduktion: Idag beräknas global mortalitet vara ungefär 9,4 miljoner varje år till följd av hypertoni; högt blodtryck. Ungefär två miljoner av befolkningen i Sverige bär på sjukdomen där sjukdomstillståndet hos majoriteten av de drabbade yttras asymtomatiskt. LÄS MER

4. 3. The Effect of Alternative Tungsten Carbide Grain Size Distribution on Microstructure and Mechanical Properties in Cemented Carbides

   Master-uppsats, KTH/Materialvetenskap

   Författare :Filip Ivarsson; [2022]
   Nyckelord :Cemented Carbides; WC Grain Size Distribution; Mechanical Properties; Microstructure Analysis; Hårdmetall; WC Kornstorleksfördelning; Mekaniska Egenskaper; Mikrostruktur Analys;

   Sammanfattning : In the constant pursuit of better-performing cemented carbides, recent studies suggest that a combination of better hardness and toughness can be obtained by changing its WC grain size distribution. As the area is still rather unexplored, this  thesis  aims  to  broaden  the  knowledge  and  answer  whether mechanical properties can be changed by changing the WC grain size distribution, in the context of mining drill bit inserts. LÄS MER

5. 4. Exploring Column Update Elimination Optimization for Spike-Timing-Dependent Plasticity Learning Rule

   Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

   Författare :Ojasvi Singh; [2022]
   Nyckelord :Spike-Timing Dependent Plasticity; neuromorphic computing; Hebbian Learning; Spiking Neural Networks; memory optimization.; Spike-Timing Beroende Plasticitet; neuromorfisk beräkning; Hebbiansk inlärning; Spiking Neural Networks; Minnes optimering;

   Sammanfattning : Hebbian learning based neural network learning rules when implemented on hardware, store their synaptic weights in the form of a two-dimensional matrix. The storage of synaptic weights demands large memory bandwidth and storage. LÄS MER

7. 5. Antenna Design and Link Performance Verification of Antennas for 5G mmWave Handheld Devices

   Master-uppsats, Lunds universitet/Institutionen för elektro- och informationsteknik

   Författare :Vinodhini Mylai Chandrasekaran; Nikhila Chinnayanapalli Ravi; [2022]
   Nyckelord :Antenna Design; mmWave frequency; 5G; FEKO; Technology and Engineering;

   Sammanfattning : The purpose of the thesis is to design a new antenna system and to verify its link performance in 5G FR2 mmWave frequency for handheld devices to enable cellular communication. The main objective is to design an antenna primarily at 28GHz and 39GHz to enhance spectrum efficiency, along with improved transmission data rates, enabling new cases like Augmented Reality (AR), Virtual Reality (VR) and many more such applications. LÄS MER