Sökning: "flavivirus"

Visar resultat 1 - 5 av 14 uppsatser innehållade ordet flavivirus.

  1. 1. Acquired and lost structure-functions of non-enveloped and enveloped viruses

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Diogo Filipe; [2022]
    Nyckelord :;

    Sammanfattning : Viruses are biological entities that constantly affect the world around us and in many cases they can harm the health of humans and negatively impact food production, in agriculture andfisheries. The project concept is that, through the structural studies of viruses that infectsimple hosts, it is possible to point out structural features that are unique and conserved inviruses, that infect human, other animals, and crops, in the same phylogenetic lineage. LÄS MER

  2. 2. In Vitro Assessment of Novel Compounds as Potential Pan-Coronavirus Therapeutics in SARS-CoV-2 and In Vitro Assessment of a Pan-Flavivirus Compound in Zika Virus

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Julia Berger; [2022]
    Nyckelord :Human coronavirus; active protease inhibitors; drug discovery; 3CLpro; Zika virus; flavivirus inhibitor; NS2B-NS3;

    Sammanfattning : Through the SARS-CoV-2 pandemic, it has become clear that the development of antivirals is essential for the health and wellbeing of the population. In this study, novel active site protease inhibitors against SARS-CoV-2 were tested for their inhibitory activity against the viral 3-Chymotrypsin like protease through the means of FRET based enzymatic assays. LÄS MER

  3. 3. Tick-Borne Encephalitis In Sweden : What Is Happening In My County Over The Past 35 Years?

    Master-uppsats, Linnéuniversitetet/Institutionen för hälso- och vårdvetenskap (HV)

    Författare :Bushra Ejaz; [2021]
    Nyckelord :Tick-borne encephalitis; ONE health; Tick-borne encephalitis vaccination; Ixodes ricinus; Roe deer; Outdoor leisure activities;

    Sammanfattning : Tick-borne encephalitis is a vector-borne zoonotic disease with more than 12,000 annual clinical reported cases globally (WHO, 2021). Tick-borne encephalitis is caused by the flavivirus and transferred by Ixodes ricinus from roe deer to human and affects the central Nervous system. LÄS MER

  4. 4. Design, expression and purification of virus-like particles derived from metagenomic studies : Virus-like Particles (VLP) of novel Partitiviridae species, Hubei.PLV 11, and novel Soutern pygmy squid flavilike virus were designed, expressed using the bac-to-bac expression system and then pruified using various methods

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Diyar Ayranci; [2021]
    Nyckelord :Virus; virus-like particles; VLP. Western Blot; SDS-PAGE; Chromatography; partitivrus; partitiviridae; flaviviridae; flavivirus; Hubei partitilike virus; Southern Pygmy Squid flavilike virus; protein purification; protein characterization; PCR; Cloning; metagenomic; strucutral biology; cryo-em; bac-to-bac expression system; vaccines; arbovirus; arthropod-borne virus;

    Sammanfattning : Viruses are entities which are made of a few genes and are reliant on obligate parasitism to propagate. Due to the obligate connection to their hosts, virus evolution is constrained to the type of host. Viruses however do transmit to evolutionary distinct hosts; in these cases, the phylogenetic relationship of the hosts usually are close. LÄS MER

  5. 5. Bats as hosts of zoonotic pathogens : potential conflicts between nature conservation and public health

    Master-uppsats, SLU/Dept. of Wildlife, Fish and Environmental Studies

    Författare :Therese Thalin; [2021]
    Nyckelord :bats; conservation; Daubenton’s bat; Myotis daubentonii; public health; vector; zoonotic pathogens;

    Sammanfattning : Bats belong to the order Chiroptera, one of the most species rich mammalian groups of Sweden, but it is also the most threatened one. Nineteen different bat species have been found in Sweden, of which 12 are red-listed. Globally rodents and bats are the animal groups known to host most zoonotic pathogens. LÄS MER