Sökning: "fluorescensmikroskopi"

Visar resultat 1 - 5 av 18 uppsatser innehållade ordet fluorescensmikroskopi.

  1. 1. Image Segmentation and Object Identification in Cancer Tissue Slides from Fluorescence Microscopy

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen Vi3

    Författare :Sebastian Eriksson; Fredrik Forsberg; [2023]
    Nyckelord :image analysis; cancer research; fluorescent microscopy; image segmentation; bildanalys; cancerforskning; fluorescensmikroskopi; bildsegmentering;

    Sammanfattning : In cancer research, there is a need to make accurate spatial measurements in multi-layered fluorescence microscopy images. Researchers would like to measure distances in and between biological objects such as nerves and tumours, to investigate questions which includes if nerve distribution in and around tumours can have a prognostic value in cancer diagnostics. LÄS MER

  2. 2. Aggregating predictions of a yeast semantic segmentation model : Reducing a pixel classifier into a binary image classifier

    Master-uppsats, KTH/Skolan för elektroteknik och datavetenskap (EECS)

    Författare :Ali Muquri; [2023]
    Nyckelord :;

    Sammanfattning : The introduction of machine learning in clinical microbiology is important for aiding clinical laboratories with highly repetitive tasks that are fatiguing, error-prone, and require long employee training time due to the complex nature of the task. A challenging task that belongs to the subareas that need assistance is yeast detection in fluorescence microscopy where various yeast morphologies exist. LÄS MER

  3. 3. Cytokine capture with beads in cytotoxicity assays in microwells

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Maxime Simon; [2023]
    Nyckelord :Microbead; Inteferon gamma; Natural Killer cells; microwell; binding-reaction model; Mikrokula; Interferon gamma; Naturliga Mördarceller; Mikrobrunn; modell för bindningsreaktion;

    Sammanfattning : Cytokines are small, secreted proteins that are important for cell signalling in theimmune system. Interferon gamma (IFN-γ) is one of the most potent cytokines thatnatural killer (NK) cells of the innate immune system secrete with both antiviral,antibacterial, and antitumoral activity. LÄS MER

  4. 4. Non-canonical amino acid incorporation as a strategy for labeling membrane bound Na+/K+-ATPase for fluorescence microscopy imaging

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Adam Johansson Holopainen; [2023]
    Nyckelord :ncAAs; fluorescence microscopy; amber suppression; nonsense suppression; Na K -ATPase; protein labeling; click chemistry; genetic code expansion; onaturliga aminosyror; fluorescensmikroskopi; Na K -ATPas; proteinmärkning; klickkemi; genetisk kodexpansion;

    Sammanfattning : Natrium-kaliumpumpen spelar en väsentlig roll i en rad fysiologiska funktioner då den upprätthåller den elektrokemiska gradienten över cellmembranet. Ytterligare så är störningar i dess funktion associerade med flera neurologiska sjukdomar. LÄS MER

  5. 5. Comparison and optimization of extracellular vesicle (EV) capturing on functional thin films for their molecular profiling

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Prattakorn Metem; [2023]
    Nyckelord :extracellular vesicle; plasmonic nanohole array; atomic force microscopy; fluorescence analysis; extracellulära vesiklar; nanohålsuppsättning; atomkraftsmikroskopi; fluorescensanalys;

    Sammanfattning : Extracellular vesicles (EVs) are lipid bilayer encapsulated nanoparticles which have emerged as an excellent source of biomarkers for multiple diseases, including cancer. However, they are highly heterogeneous in their molecular compositions which remains a major challenge hindering the utilization of their biomarker potential. LÄS MER