Sökning: "fluorescent ligands"

Hittade 2 uppsatser innehållade orden fluorescent ligands.

1. 1. Fluorescent molecules as probes for characterization of amyloid β fibrils

   Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

   Författare :Denisse Marginean; Ebba Hellstrand; [2021]
   Nyckelord :Alzheimer s disease; amyloid beta; amyloid; fluorescent probes; fluorescent ligands;

   Sammanfattning : Alzheimer’s Disease (AD) is the leading cause of dementia in the world and the World Health Organization has recognized AD as a global public health priority. One of the pathological hallmarks of AD is amyloid plaques formed from amyloid β (Aβ) fibrils. Aβ is formed when amyloid precursor protein is cleaved by secretase enzymes. LÄS MER

3. 2. Synthesis of proteophenes that can be utilized as fluorescent ligands for biological targets

   Master-uppsats, Linköpings universitet/Kemi

   Författare :Linnea Björk; [2019]
   Nyckelord :Fluorescent probes; Neuredegenerative diseases; Luminescent Conjugated Oligothiophenes; Protein misfolding; Aggregates; Amyloids; Alzheimer’s disease; Aβ-plaque;

   Sammanfattning : Small fluorescent probes are important tools when studying protein aggregates involved in different neurodegenerative diseases, such as Alzheimer’s disease. Luminescent conjugated oligothiophenes have been developed and shown to be excellent ligands when studying morphology among amyloids, due to their conjugated thiophene backbone that provides them with unique photophysical properties. LÄS MER