Sökning: "fluorescent probes"

Visar resultat 1 - 5 av 17 uppsatser innehållade orden fluorescent probes.

  1. 1. Quantification of DNA Nanoballs Using Image Processing Techniques

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen Vi3

    Författare :Sara Lindberg; [2023]
    Nyckelord :image analysis; fluorescence microscopy; quantification; DNA; rolling circle amplification; machine learning; deep learning; transfer learning; neural networks;

    Sammanfattning : In gene editing, it is important to identify the number of edited and unedited nucleic acids in the development of new therapies and drugs. Countagen is developing a technology for accelerating genomic research and their product is called GeneAbacus. LÄS MER

  3. 2. Functionalization and Evaluation of Nanoparticle Probes for the Development of a 14-Plex Diagnostic assay

    Master-uppsats, KTH/Kemi

    Författare :Samuel Narmack; [2021]
    Nyckelord :Functionalization; multiplex; probing; diagnostics; nanoparticles; Funktionalisering; multiplexera; sonder; diagnostik; nanopartiklar;

    Sammanfattning : Detta projekt var ett samarbete mellan Aplex Bio AB och Scilifelab. Projektets mål var att utveckla en molekylär diagnostisk panel med förmågan att detektera och diskriminera mellan 14 olika typer av patogener. Projektet innehåller 4 kapitel med fokus på olika mål. LÄS MER

  4. 3. Fluorescent molecules as probes for characterization of amyloid β fibrils

    Kandidat-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Denisse Marginean; Ebba Hellstrand; [2021]
    Nyckelord :Alzheimer s disease; amyloid beta; amyloid; fluorescent probes; fluorescent ligands;

    Sammanfattning : Alzheimer’s Disease (AD) is the leading cause of dementia in the world and the World Health Organization has recognized AD as a global public health priority. One of the pathological hallmarks of AD is amyloid plaques formed from amyloid β (Aβ) fibrils. Aβ is formed when amyloid precursor protein is cleaved by secretase enzymes. LÄS MER

  5. 4. The use of graphene quantum dots as detection elements in nanomaterials-based sensors for forensic applications

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Xiaofan Ma; [2021]
    Nyckelord :Graphene Quantum Dots; Amphetamine; Cocaine; Chemical Sensor; Forensic Drugs; Grafenkvantprickar; amfetamin; kokain; kemisk sensor; rättsmedicinska läkemedel;

    Sammanfattning : The large-scale abuse and addiction of narcotics such as amphetamine and cocaine have become a global problem. In this project, we innovatively use graphene quantum dots (GQDs) as a fluorescent sensor to detect and quantify amphetamine and cocaine. This technology will have broad forensic application prospects. LÄS MER

  7. 5. Characterization of the fusion protein mNG-Aβ1-42 as a fluorescence reporter probe for amyloid structure

    Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Linnéa Fredén; [2020]
    Nyckelord :Alzheimer’s Disease AD ; Amyloids; Aβ; fusion protein; mNeonGreen; mNG-Aβ1-42; Crystallization; mouse brain tissue; human brain tissue; amyloid fluorescent probes;

    Sammanfattning : Alzheimer’s Disease, also called AD, is a horrible, degenerative brain disease that more than 35 million people over the world have. Today, there is no cure for this disease, only treatments that are temporarily relieving the symptoms. The two proteins that is thought to be the main cause of AD is amyloid β (Aβ) and tau. LÄS MER