Sökning: "gene regulatory networks"

Visar resultat 6 - 10 av 14 uppsatser innehållade orden gene regulatory networks.

1. 6. Identifying Cell Reprogramming Roadblocks by Modelling Induced Pluripotency with Boolean Networks and Dynamical Systems

   Master-uppsats, Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

   Författare :Johannes Isaksson; [2018]
   Nyckelord :Stem cells; pluripotency; pluripotent; reprogramming; iPS; induced pluripotency; Boolean; dynamical systems; network.; Medicine and Health Sciences;

   Sammanfattning : The generation of induced pluripotent stem (iPS) cells from differentiated cells is a process of great scientific interest due to the medical potential of such cells. This process (called 'reprogramming' of cells) is however notoriously inefficient and still not very well understood. LÄS MER

3. 7. Robust Community Predictions of Hubs in Gene Regulatory Networks

   Master-uppsats, Linköpings universitet/Bioinformatik

   Författare :Julia Åkesson; [2018]
   Nyckelord :Biological systems; Biological networks; Network inference; Gene regulatory networks; Hubs; Master regulators; Community predictions; Bioinformatics;

   Sammanfattning : Many diseases, such as cardiovascular diseases, cancer and diabetes, originate from several malfunctions in biological systems. The human body is regulated by a wide range of biological systems, composed of biological entities interacting in complex networks, responsible for carrying out specific functions. LÄS MER

4. 8. The Function of FoxB During Limb Development and Axis Formation in the Spider Parasteatoda tepidariorum

   Master-uppsats, Uppsala universitet/Institutionen för geovetenskaper

   Författare :Miriam Heingård; [2017]
   Nyckelord :spider; RNA interference; FoxB; ventral patterning; appendage; Drosophila; spindel; RNA interferens; FoxB; ventral; lemmar; Drosophila;

   Sammanfattning : Arthropods are the most diverse and speciose group of animals on the planet. A key factor in their success is the adaptation of various appendages to new functions and environments, resulting in radically different morphologies. To understand this diversity, it is important to study the underlying genetic mechanisms. LÄS MER

5. 9. Parameter optimization of linear ordinary differential equations with application in gene regulatory network inference problems

   Master-uppsats, KTH/Numerisk analys, NA

   Författare :Yue Deng; [2014]
   Nyckelord :Ordinary differential equations; parameter optimization; gene regulatory network inference; DREAM4 project;

   Sammanfattning : In this thesis we analyze parameter optimization problems governed by linear ordinary differential equations (ODEs) and develop computationally efficient numerical methods for their solution. In addition, a series of noise-robust finite difference formulas are given for the estimation of the derivatives in the ODEs. LÄS MER

7. 10. Robustness of Bistable Switches in Gene Regulatory Networks

   Uppsats för yrkesexamina på avancerad nivå, KTH/Reglerteknik

   Författare :Benjamin Mairesse; [2007]
   Nyckelord :;

   Sammanfattning : Gene expression often reacts to intra- and extra-cellular signals in an ”on-off” switchlike manner. These switches, which display hysteresis, correspond to multiple steady-state solutions of the gene regulatory network and are created through saddle-node bifurcations at which a single real eigenvalue of the local Jacobian crosses the imaginary axis for changes in some system parameter. LÄS MER