Sökning: "genome scan"

Visar resultat 1 - 5 av 7 uppsatser innehållade orden genome scan.

  1. 1. Identification of de novo Transcription Factor Binding Motifs Created by Cancer-related Mutations

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Siqi Li; [2022]
    Nyckelord :transcription factor binding motifs; funMotifs; PCAWG; mutations; de novo motifs;

    Sammanfattning : In many countries, cancer is one of the biggest threats for citizens’ health, especially among aged people. Genomic mutations play a crucial role in cancer cell development. In previous decades, cancer research has been mainly focused on mutations in coding regions. LÄS MER

  3. 2. Exploring methods for detecting super-spreaders using molecular data : A literature study and case study of VTEC O157:H7 in dairy calves

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Amanda Wallskog; [2022]
    Nyckelord :Super-spreaders; Super-shedders; outbreaker2; phybreak; VTEC O157:H7;

    Sammanfattning : Verotoxin-producing Escherichia coli (VTEC) of serotype O157:H7 is a pathogen causing illness in humans worldwide. The path and nature of transmission from and among cattle is important knowledge when it comes to preventing cases of disease in humans. LÄS MER

  4. 3. A mixed clinicopathological and molecular proxy of homologous recombination deficiency in triple negative breast cancer

    Master-uppsats, Lunds universitet/Examensarbeten i bioinformatik

    Författare :Elise Walford; [2021]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Clinical models are increasingly employed in medical science as either diagnostic or prognostic aids. Machine-learning methods are able to draw links in large data that can be used to predict patient risk and allow more informed decisions regarding treatment and medication intervention. LÄS MER

  5. 4. Genetic diversity and hardiness in Scots pine from Scandinavia to Russia

    Master-uppsats, Umeå universitet/Institutionen för ekologi, miljö och geovetenskap

    Författare :Jenny Olsson; [2019]
    Nyckelord :Pinus sylvestris; recolonization history; genetic diversity; cold hardiness; clinal variation;

    Sammanfattning : The postglacial recolonization of northern Europe supposedly originated from Western Europe and the Russian Plain, however, recent molecular and macrofossil-based investigations suggest that the history may be more complex than previously thought. This study aims to investigate the genetic diversity and population structure of Scots pine from Scandinavia to Russia to re-evaluate its recolonization history, and to examine whether the pattern of spatial genetic diversity has any adaptive significance. LÄS MER

  7. 5. Evolutionary history and local adaptation in Scottish populations of Populus tremula

    Master-uppsats, SLU/Dept. Of Plant Biology

    Författare :Jonathan R. Wilson; [2019]
    Nyckelord :local adaptation; population structure; selective sweep; synteny;

    Sammanfattning : From a subset of P. tremula samples taken from across Europe and China, principal component analysis of genetic variation indicated population structure in the Scottish population compared with the rest of Eurasia. LÄS MER