Sökning: "genome-editing"

Visar resultat 1 - 5 av 17 uppsatser innehållade ordet genome-editing.

1. 1. Establishing novel approaches for assessing safety of genome-editing-based therapeutics

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Noorul Shaheen Sheikh Farid; [2023]
   Nyckelord :;

   Sammanfattning : Genome editing based medicines are a new therapeutic modality being developed. They show great promise for a spectrum of genetic diseases lacking conventional treatment strategies. A major obstacle that prevents such therapies to reach the clinic is their safety. LÄS MER

3. 2. Compounds screening for the identification of novel drug to improve the Knock in efficiency mediated by CRISPR-Cas9

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

   Författare :Evangelia Anagnostou; [2023]
   Nyckelord :Genome editing; Knock in; HDR; CRISPR-Cas9; screening; NHEJ;

   Sammanfattning : Genome editing is an exciting field that allows for the precise modification of an organism's DNA. One of the most advanced tools in this area is CRISPR/Cas9 (Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9), which creates a DSB (Double-strand break) at a specific location in the genome. LÄS MER

4. 3. mRNA-based pharmaceuticals : A literature study based on current knowledge of mRNA

   Kandidat-uppsats, Uppsala universitet/Institutionen för kemi - Ångström

   Författare :Alicia Andersson; Isabella Åkerfeldt; Amanda Borgenstam; Ellinor Olsson; Adam Nyström; [2022]
   Nyckelord :mRNA-pharmaceuticals; mRNA therapies; mRNA vaccines; mRNA components; mRNA design; and mRNA applications.;

   Sammanfattning : This literature study provides a comprehensive overview of the current knowledge of mRNA-based pharmaceuticals, technologies and applications.  mRNA-based pharmaceuticals have newly been bought into focus as a potential brand-new drug class and many believe that it has the potential to transform areas of medicine. LÄS MER

5. 4. CRISPR AND THETREATMENT/EN DISTINCTION : On Vagueness, Borderline Cases and Germline Genome Editing

   Kandidat-uppsats, Umeå universitet/Institutionen för idé- och samhällsstudier

   Författare :Ellen Svensson; [2021]
   Nyckelord :CRISPR; Treatment; Enhancement; Vagueness; Borderline cases; Slippery slope; Germline genome editing; GGE; Gene editing; Distinction; Ethics; Radical Enhancement; Human Nature; Eugenics;

   Sammanfattning : In this thesis, I argue that the treatment/enhancement distinction that is central to the ethical debate concerning germline genome editing and CRISPR is too vague to be ethically and normatively guiding. The problem of vagueness is twofold, being both a semantic and epistemic issue. LÄS MER

7. 5. The ethics of genome editing of animals

   Master-uppsats, SLU/Dept. of Animal Breeding and Genetics

   Författare :Annelien Prosman; [2021]
   Nyckelord :ethics; genome editing; animals;

   Sammanfattning : In the Western culture nowadays, a large number of animals is used for food production and because of the growing world population, the demand for animal products is increasing even more. Since the planet has its environmental boundaries, it is important that these products are produced sustainably to minimize negative environmental impacts. LÄS MER