Sökning: "glioma"

Visar resultat 1 - 5 av 26 uppsatser innehållade ordet glioma.

  1. 1. Characterization of the immunomicroenvironment of glioblastoma : Optimization of an antibody panel for detection of glioblastoma TME cells and effect of C3 on glioma cells.

    Kandidat-uppsats, Malmö universitet/Fakulteten för hälsa och samhälle (HS)

    Författare :Julia Wahldén; [2023]
    Nyckelord :Brain; cancer; glioblastoma; immune cells; immunofluorescence; tumor microenvironment; Cancer; glioblastom; immunceller; immunofluorescens; hjärnan; tumörmikromiljö;

    Sammanfattning : Glioblastoma (GBM) is the most common primary brain tumor in adults and represents one of the most aggressive tumor types. Despite treatment GBM remains incurable and when treated the tumor recurs more aggressive and treatment resistant than before. LÄS MER

  2. 2. Identification of Immunological Targets for Brain Cancer Immunotherapy

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Zhenda Wang; [2022]
    Nyckelord :Cancer immunotherapy; brain cancer; neoantigen; MHC HLA; TCR;

    Sammanfattning : Background Cancer immunotherapy has yielded many successes. Yet to some hard-to-treat brain tumors, such as glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), it still lacks substantial improvement. Neoantigens resulting from mutations in malignant cells are the key targets for employing adoptive cell therapies. LÄS MER

  3. 3. Investigating the subcellular localisation and function(s) of dystrophin protein Dp71 isoforms in glioma

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Abdullah Al-Ani; [2022]
    Nyckelord :DMD; Dp71; glioblastoma; Lamin B1; cell migration;

    Sammanfattning : The Dp71 protein is the most expressed product of the DMD gene in the nervous system. Mutation in the region codes dystrophin protein (Dp71) linked to cognitive disturbances in Duchenne muscular dystrophy (DMD) patients. There is growing evidence that the gene is contributing to the development of Central Nervous System related cancers. LÄS MER

  4. 4. Brain Tumor Grade Classification in MR images using Deep Learning

    Master-uppsats, Linköpings universitet/Statistik och maskininlärning

    Författare :Eleftheria Chatzitheodoridou; [2022]
    Nyckelord :brain tumor; glioma; magnetic resonance imaging; deep learning; brain tumor grade classification; convolutional neural network; transfer learning; explainability; multi-class classification;

    Sammanfattning : Brain tumors represent a diverse spectrum of cancer types which can induce grave complications and lead to poor life expectancy. Amongst the various brain tumor types, gliomas are primary brain tumors that compose about 30% of adult brain tumors. LÄS MER

  5. 5. Classification of brain tumors in weakly annotated histopathology images with deep learning

    Master-uppsats, Linköpings universitet/Statistik och maskininlärning

    Författare :Dávid Hrabovszki; [2021]
    Nyckelord :medical imaging; deep learning; glioblastoma; tcga; brain tumor; weakly supervised; histopathology; digital pathology; histology;

    Sammanfattning : Brain and nervous system tumors were responsible for around 250,000 deaths in 2020 worldwide. Correctly identifying different tumors is very important, because treatment options largely depend on the diagnosis. LÄS MER