Sökning: "human brain tissue"

Visar resultat 1 - 5 av 35 uppsatser innehållade orden human brain tissue.

  1. 1. Anatomical segmentation of the human brain: comparative assessment of two automatic methods

    Master-uppsats,

    Författare :Carl von Dorrien; [2023-08-22]
    Nyckelord :Medical physics; MAPER; FreeSurfer; FastSurfer; Automatic brain segmentation; MRI; Deep Neural Network; Brain;

    Sammanfattning : Magnetic Resonance Imaging (MRI) is a robust and versatile imaging modality and an integral component of a lot of studies, especially when performing quantitative analysis. MRI is the preferred method of imaging the brain because of its excellent soft tissue contrast. LÄS MER

  3. 2. Chromatin accessibility analysis of spaceflight mouse brains using ArchR

    Master-uppsats, KTH/Genteknologi

    Författare :Raphaël Mauron; [2023]
    Nyckelord :Single nuclei ATAC-sequencing; Space Biology; DNA Chromatin accessibility; Neurodegenerative; ArchR; ATAC-sekvensering av enskilda kärnor; rymdbiologi; tillgänglighet av DNA kromatin ; neurodegenerativa sjukdomar; ArchR;

    Sammanfattning : Mänsklig utforskning av månen och Mars innebär stora utmaningar för människans fysiologi och hälsa på grund av de unika miljöfaktorer som följer av långvariga rymduppdrag. Rymdbiologiska experiment har blivit ett viktigt verktyg för att studera effekterna som mikrogravitation och rymdstrålning har på levande organismer, i syfte att förstå och minska dessa utmaningar. LÄS MER

  4. 3. Quantitative susceptibility mapping of the knee: A comparison of approaches for addressing fatty tissue

    Master-uppsats, Lunds universitet/Sjukhusfysikerutbildningen

    Författare :Cornelia Säll; [2023]
    Nyckelord :Medicine and Health Sciences;

    Sammanfattning : Background/purpose Quantitative susceptibility mapping (QSM) is an MRI-based post processing technique to evaluate the magnetic susceptibility, χ, of human tissue using phase data. While brain imaging has been the most common application, other areas have also raised interest. LÄS MER

  5. 4. Developing a Method to Study the Impact of Microbial DNA on the Brain Related to Alzheimer’s Disease – Can Food Make a Change?

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Fuh-Tzu Yang; [2022]
    Nyckelord :DNA extraction; Microbiome DNA enrichment; Host DNA depletion; 16S rRNA sequencing; Alzheimer’s disease; Gut-brain axis; Microbiota; Microbial DNA; Black currant; Applied Nutrition and Food Chemistry; Medicine and Health Sciences;

    Sammanfattning : Understanding the gut-brain-microbiota axis can help us provide a new tool to manage conditions such as Alzheimer’s. However, a major challenge is selectively amplifying the bacterial DNA which is present at a much lower level than the host DNA. LÄS MER

  7. 5. DEVELOPMENT, VALIDATION AND APPLICATION OF A METHOD FOR DETERMINATION OF METABOLITE CONCENTRATIONS WITH PRECLINICAL MAGNETIC RESONANCE SPECTROSCOPY

    Master-uppsats,

    Författare :Lukas Lundholm; [2021-05-10]
    Nyckelord :Medical physics; Basis sets; Metabolites; Quantification; Animal study; MRS;

    Sammanfattning : Background: Information on the metabolic content in tissue has diagnostic and prognostic value when examining for example cancer and diseases of the brain. MR spectroscopy is a non-invasive method that allows quantification of metabolite concentrations in vivo, without the use of ionizing radiation, which makes the method highly attractive for both research and clinical applications. LÄS MER