Sökning: "human hepatocytes"

Visar resultat 1 - 5 av 7 uppsatser innehållade orden human hepatocytes.

  1. 1. Synthesis and analysis of potential metabolites of ADB-5´Br-BUTINACA

    Kandidat-uppsats, Linköpings universitet/Kemi

    Författare :Alaa Malekshahineia; [2023]
    Nyckelord :metabolites; NPS; synthetic cannabinoids;

    Sammanfattning : In recent years, there has been a rise in the use of New Psychoactive Substances (NPS) that mimic the effects of controlled drugs and licensed medicines, which have become a significant public health concern globally. Synthetic cannabinoids, a rapidly expanding category of NPS, with much higher potency and binding affinity to the cannabinoid receptors than ∆9-tetrahydrocannabinol (THC), have led to serious psychiatric complications and other adverse effects. LÄS MER

  3. 2. KARAKTERISERING AV EN PLASMABUREN SIGNALMOLEKYL SOM STIMULERAR FRISÄTTNING AV SFINGOSIN-1-FOSFAT FRÅN RÖDA BLODKROPPAR

    Kandidat-uppsats, Göteborgs universitet / Instiutionen för biologi och miljövetenskap

    Författare :Matilda Nordström; [2022-10-19]
    Nyckelord :Sphingosine-1-phosphate S1P ; Red blood cells; Plasma; Signaling molecule; LC-MC;

    Sammanfattning : Bioactive sphingolipid Sphingosine-1-phosphate (S1P) is found in blood, where it plays an important part in, for example, angiogenesis. S1P is synthesized in hepatocytes, vascular endothelium and blood cells, then transported with high-density lipoprotein (HDL) or albumin in plasma. S1P can accumulate in, and be released from red blood cells. LÄS MER

  4. 3. Study of up-regulated genes in gene clusters during formation of mature hepatocytes from human induced pluripotent stem cells to identify transcription factors and mirnas

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Suraj Thomas Alexander; [2021]
    Nyckelord :;

    Sammanfattning : The multifunctional purpose of hepatocytes, the functional liver cells within the metabolic, endocrine and secretory functions highlights key importance in emphasizing the research and treatment methods that utilize these cells. Forming 80% of the liver's cells, hepatocytes are involved in many of the primary functions of the liver including the delivery of immune response against pathogens and aiding in the detoxification of drugs. LÄS MER

  5. 4. Deep convolutional neural networks accurately predict the differentiation status of human induced pluripotent stem cells

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Katarzyna Marzec-Schmidt; [2020]
    Nyckelord :;

    Sammanfattning : Rapid progress of AI technology in the life science area is observed in recent years. Convolutionalneural network (CNN) models were successfully applied for the localization and classification of cellson microscopic images. Induced pluripotent stem cells are one of the most important innovations inbiomedical research and are widely used, e.g. LÄS MER

  7. 5. New applications of Antrad Medical's thawing technology : Applications within the clinical and laboratory segment

    Kandidat-uppsats, KTH/Skolan för teknik och hälsa (STH)

    Författare :Malin Truvé; Johanna Kilegran; [2016]
    Nyckelord :Antrad Medical; thawing; thawing methods; thawing device; heating; stem cells; cryoprecipitate; human hepatocytes; API; BDS; intermediate; pharmaceuticals; Antrad Medical; upptining; upptiningstekniker; upptiningsapparat; uppvärmning; stamceller; kryoprecipitat; humana hepatocyter; läkemedel;

    Sammanfattning : Antrad Medical has developed an ultra-fast blood plasma thawing device named UFT100. The method is based on thawing with an oscillating electrical field and unlike water baths it is a dry method. Fast and homogeneous thawing is achieved. LÄS MER