Sökning: "human malignant melanoma"

Hittade 4 uppsatser innehållade orden human malignant melanoma.

  1. 1. CRISPR Screen to Identify Genes Regulating Melanoma Cell Invasiveness

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Emma Kroon; [2023]
    Nyckelord :CRISPR-Cas9; gene knockout; viral packaging; transduction; invasionstest; CRISPR-Cas9; genknockout; viruspackning; transduction; invasion assay;

    Sammanfattning : Maligna cancerceller har förmågan att sprida sig okontrollerat i kroppen och metastasera till avlägsna organ. Kritiskt i metastaserings processen är cancercellers förmåga att invadera närliggande vävnader innan de sprider sig vidare ut i kroppen. LÄS MER

  2. 2. Segmentation and Prediction of Mutation Status of Malignant Melanoma Whole-slide Images using Deep Learning

    Master-uppsats, Lunds universitet/Avdelningen för Biomedicinsk teknik

    Författare :Elin Johansson; Fanny Månefjord; [2021]
    Nyckelord :deep learning; image analysis; malignant melanoma; tissue segmentation; mutation classification; Inception v3; Technology and Engineering;

    Sammanfattning : Malignant melanoma is an aggressive type of skin cancer. Gene mutations can make the disease progress faster, but specialised treatment exists. Today, gene mutations are detected with DNA-analysis which is costly and time-consuming. LÄS MER

  3. 3. Intracellular half-life of cisplatin in malignant cells : A kinetic study of the decline rate of intracellular cisplatin concentration in in-vitro grown cells determined by LC-ICP-MS following exposure to clinically relevant cisplatin doses

    Master-uppsats, Kemiska institutionen

    Författare :Liem Nguyen Van; [2011]
    Nyckelord :;

    Sammanfattning : Cisplatin is a common cancer therapy substance used against several types of malignant tumors and often shows great efficiency. The most important tumour killing mechanism is believed to be formation of Pt-DNA adducts. It is however a common phenomenon that tumors develop resistance causing inefficient treatment. LÄS MER

  4. 4. Kvantitativ RT-PCR-analys för detektion av pigmentrelaterade transkript i hårrötter från hund

    L3-uppsats, SLU/Dept. of Clinical Sciences

    Författare :Ulrika Falkenö; [2007]
    Nyckelord :pigment; hårrötter; hund; kvantitativ RT-PCR; malignt melanom;

    Sammanfattning : Malignant melanoma represents 4-7% of all canine neoplasms and they are the most common malignant tumors of the oral cavity and digits. These tumors are often aggressive and metastasize quickly. To date there is no effective treatment and survival times are short. Most dogs are euthanized due to complications caused by metastases. LÄS MER