Sökning: "hyaluronic"

Visar resultat 1 - 5 av 19 uppsatser innehållade ordet hyaluronic.

  1. 1. Synovial fluid components as synergistic lubricants in articular joint models

    Master-uppsats, KTH/Kemi

    Författare :Sixuan Li; [2019]
    Nyckelord :synergistic lubrication; synovial fluid; biolubrication; DPPC; hyaluronic acid; Mini-Traction Machine; macro- and microscale; profilometer;

    Sammanfattning : The excellent lubrication present within mammalian synovial joints attracted scientific interest, and some close-to-realistic models were applied to study the mechanism in vitro. In this project, the synergistic lubrication of synovial fluid was investigated by using 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine (DPPC), hyaluronic acid (HA), and phosphate-buffered saline (PBS buffer) to mimic the synovial fluid. LÄS MER

  2. 2. Optimization of Acidic Degradation of Hyaluronic Acid using Design of Experiments

    Master-uppsats, Linköpings universitet/Teknisk biologi

    Författare :Emma Sandqvist Wedin; [2019]
    Nyckelord :Hyaluronic Acid; Molecular Weight; Acidic Degradation; Heterogeneous Degradation; Robustness Testing; Degradation Constant; Design of Experiments; Degradation; DoE;

    Sammanfattning : Hyaluronic acid (HA) is an unbranched polysaccharide consisting of the repeating disaccharide unit β(1→4)-GlcA-β(1→3)-GlcNAc and is a naturally occurring biopolymer in bacteria and vertebras. HA is predominantly found in the extracellular matrix (ECM) and the in vivo function of HA can vary depending on molecular weight (Mw) for instance high Mw HA is reported to be anti-angiogenic while low Mw HA induces angiogenesis. LÄS MER

  3. 3. A rheological study of hyaluronan and sodium hydroxide at different concentrations

    Kandidat-uppsats, Uppsala universitet/Institutionen för teknikvetenskaper; Uppsala universitet/Institutionen för teknikvetenskaper; Uppsala universitet/Institutionen för teknikvetenskaper; Uppsala universitet/Institutionen för teknikvetenskaper; Uppsala universitet/Institutionen för teknikvetenskaper

    Författare :Natalia Gentek; Melissa Jöe; Sofia Lindell; Karin Norgren; Ellen Sjövall; [2018]
    Nyckelord :hyaluronan; hyaluronic acid; sodium hydroxide; rheology; fluid; elastic modulus; loss modulus;

    Sammanfattning : This thesis examines how the rheological properties change depending on the composition of hyaluronan, HA and sodium hydroxide, NaOH. This was performed to see if there was any relationship between the rheological properties of a sample depending on different compositions of HA and NaOH. LÄS MER

  4. 4. Hyaluronsyra i ledbrosk och ledvätska i en frisk led samt vid osteoartrit hos häst

    Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Karolina Mörk Englund; [2018]
    Nyckelord :häst; hyaluronsyra; osteoartrit; ledinflammation;

    Sammanfattning : Hälta är idag den vanligaste orsaken till att hästägare uppsöker veterinär med sina hästar. Många av dessa hästar får diagnosen osteoartrit. Osteoartrit är en kronisk låg-gradig inflammatorisk sjukdom som leder till en obalans mellan uppbyggande och nerbrytande processer i leden. LÄS MER

  5. 5. Mapping the intrinsic viscosityof hyaluronic acid at high concentrations of OH-

    Kandidat-uppsats, Uppsala universitet/Institutionen för teknikvetenskaper

    Författare :Victor Spelling; Mathias Axelsson; Lovisa Ringström; Johanna Munck af Rosenschöld; Anton Lindblad; [2017]
    Nyckelord :Alkaline solution; Degradation; Extrapolation; Hyaluronic acid; Intrinsic viscocity; Macromolecules; Polymer; Regression; Sodium hydroxide; Ubbelohde capillary viscometry;

    Sammanfattning : Hyaluronic acid is commonly used in dermatological fillers in the form of gels. It is established how these gels' firmness is affected by the amount of cross linker and hyaluronic acid respectively. However, the effect of hydroxide ions in solution is rather unknown. LÄS MER