Sökning: "immunogenicity"

Visar resultat 1 - 5 av 12 uppsatser innehållade ordet immunogenicity.

  1. 1. Characterization of Antigenic Properties of Two Immunogenic Proteins of Streptococcus pneumoniae 

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Mawj Jasimalsalih; [2023]
    Nyckelord :Immunogenic Proteins; PrsA; MalX; Membrane Vesicles; Protein Properties; Streptococcus pneumoniae virulence factors;

    Sammanfattning : The bacterium Streptococcus pneumoniae (pneumococcus), is considered to be a leading cause of morbidity and mortality globally, particularly in infants and the elderly. It is one of the most frequent causes of respiratory tract infections, which sporadically have the potential to develop into serious invasive symptoms including sepsis and meningitis. LÄS MER

  2. 2. Har högdos, intradermalt influensavaccintillräckligt god effekt, immunogenicitet ochsäkerhet hos äldre? : En litteraturstudie om effekten, immunogeniciteten och säkerhetav högdos influensavaccin och intradermal injektion hos äldre.

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Nesren Alkadour; [2023]
    Nyckelord :Influensavaccin; intradermalt; högdos; äldre.;

    Sammanfattning : There are four different types of influenza virus: A, B, C and D which cause influenza.Generally, influenza virus A, B and C infects humans. Rarely, influenzavirus D occursin humans, but it often infects animals. LÄS MER

  3. 3. Automated Decellularization of Heart Valves

    Kandidat-uppsats, Lunds universitet/Avdelningen för Biomedicinsk teknik

    Författare :Filip Nyberg; Brendan Carlson; [2022]
    Nyckelord :Technology and Engineering;

    Sammanfattning : Abstract—For those living today with severely malfunctioning heart valves, replacement is the only available treatment. Patients are today typically offered either mechanical valves, xenograft or allograft. Decellularized heart valves have the potential of becoming one of the standard alternatives for such heart valve transplants. LÄS MER

  4. 4. Evaluation of the immunogenicity of SARS-CoV-2 B cell epitopes

    Master-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Sofia Hogander; [2022]
    Nyckelord :SARS-CoV-2; peptide vaccine; B cell epitope; ELISA; solid phase peptide synthesis;

    Sammanfattning : Background: The COVID-19 pandemic is caused by the SARS-CoV-2 virus, which enter the host cells through interactions between the receptor-binding domain (RBD) on the S-protein and the ACE-2 receptor on the host cell. A novel type of vaccine strategy is peptide vaccines, with great potential as a faster and more selective approach to conventional vaccine development. LÄS MER

  5. 5. Development of a reporter gene assay on an automated platform

    Master-uppsats, Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

    Författare :Fanny Redin; [2021]
    Nyckelord :Reporter gene assay; Automation; Svar Life Science; Immunogenicity; TNF-alpha; Applied biochemistry; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : Biological drugs have the potential to trigger unwanted immunogenic responses in patients which might affect the efficacy and safety of the treatment. Evaluating the immunogenicity throughout the drug development process is therefore crucial. LÄS MER