Sökning: "immunotherapy"

Visar resultat 11 - 15 av 55 uppsatser innehållade ordet immunotherapy.

  1. 11. Identification of Immunological Targets for Brain Cancer Immunotherapy

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Zhenda Wang; [2022]
    Nyckelord :Cancer immunotherapy; brain cancer; neoantigen; MHC HLA; TCR;

    Sammanfattning : Background Cancer immunotherapy has yielded many successes. Yet to some hard-to-treat brain tumors, such as glioblastoma multiforme (GBM) and diffuse intrinsic pontine glioma (DIPG), it still lacks substantial improvement. Neoantigens resulting from mutations in malignant cells are the key targets for employing adoptive cell therapies. LÄS MER

  3. 12. Evaluating LOAd703 in combination with chemotherapeutic agents in ovarian cancer

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Jonas Härdin; [2022]
    Nyckelord :Clinical Immunology; Immunotherapy; LOAd; Ovarian Cancer; Oncology; Virus;

    Sammanfattning : Ovarian cancer is a disease with a high rate of mortality where the need for novel treatments will increase in the near future as older and populous generations reach the age where the cancer is usually diagnosed. Once treated, ovarian cancer tends to recur and display a newfound resistance against the platinum-based chemotherapeutic drugs that are used to treat the disease. LÄS MER

  4. 13. Improving antibody-based immunotherapy protocols in vitro : Study on optimization of antitumor immunity by antibody-dependent phagocytosis with the monoclonal antibody rituximab

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Giovanni Ferro; [2022]
    Nyckelord :;

    Sammanfattning : The monoclonal antibody Rituximab (RTX) has been widely and successfully used to treat non-Burkitt B cell lymphoma in human patients. The combination of immunotherapy with low-dose chemotherapy has increased the success of the treatment and translated into increased patients’ survival. LÄS MER

  5. 14. mRNA-based pharmaceuticals : A literature study based on current knowledge of mRNA

    Kandidat-uppsats, Uppsala universitet/Institutionen för kemi - Ångström

    Författare :Alicia Andersson; Isabella Åkerfeldt; Amanda Borgenstam; Ellinor Olsson; Adam Nyström; [2022]
    Nyckelord :mRNA-pharmaceuticals; mRNA therapies; mRNA vaccines; mRNA components; mRNA design; and mRNA applications.;

    Sammanfattning : This literature study provides a comprehensive overview of the current knowledge of mRNA-based pharmaceuticals, technologies and applications.  mRNA-based pharmaceuticals have newly been bought into focus as a potential brand-new drug class and many believe that it has the potential to transform areas of medicine. LÄS MER

  7. 15. Biophysical analysis of Immunotherapy and Cancer modeling

    Master-uppsats, Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation; Lunds universitet/Institutionen för astronomi och teoretisk fysik - Genomgår omorganisation

    Författare :Simon Tropp; [2022]
    Nyckelord :Immunotherapy; Cancer; Tumors; Immune cells; T cells; Cancer prognostics; Cancer models; Cell distribution; Physics and Astronomy;

    Sammanfattning : Accounting for 10 million deaths and 20 million new cases every year, cancer is one of the most common causes of death. The interest in trying to understand this lethal disease using mathematical models has increased steadily for many decades. Methods for boosting the immune system to better fight cancer (immunotherapy) have also been long present. LÄS MER