Sökning: "insulin signaling"

Visar resultat 1 - 5 av 12 uppsatser innehållade orden insulin signaling.

  1. 1. Polycystic ovary syndrome : A Drosophila Melanogaster Melanogaster disease model induced by DHT and/or high sugar diet

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för hälsa och lärande

    Författare :Andreas Mlekov Andersson; [2019]
    Nyckelord :Polycystic ovary syndrome; PCOS; DHT; high sugar diet; drosophila melanogaster;

    Sammanfattning : Polycystic ovary syndrome is an endocrine disorder with symptoms of hyperandrogenism, insulin-resistance and anovulation in women which creates a disposition for other disorders, like Type 2 Diabetes. Drosophila Melanogaster flies have short generation, low cost-management and share several signaling pathways with humans and are therefore an excellent tools to study disease aetiology – yet no such model exists for PCOS. LÄS MER

  3. 2. Mathematical modeling of adrenaline-induced adiponectin secretion in white adipocytes

    Master-uppsats, Linköpings universitet/Avdelningen för medicinsk teknik

    Författare :Christian Simonsson; [2018]
    Nyckelord :Systems Biology; Mathematical Modeling; Adiponectin; Adiponectin secretion; White Adipocytes; Adrenaline-induced adiponectin secretion;

    Sammanfattning : There is an ongoing worldwide obesity epidemic. As a consequence, prevalence of obesity- related diseases and conditions are rapidly increasing. One of these related conditions is type 2 diabetes (T2D), which alone caused 1.5 million deaths in 2012. LÄS MER

  4. 3. Metabol inflammation vid övervikt

    Kandidat-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Albin Hilmersson; [2018]
    Nyckelord :övervikt; inflammation; metainflammation;

    Sammanfattning : Kroniskt överintag av näringsämnen kan leda till övervikt och förändring av fettvävnadens metabola och endokrina funktion. Detta kan resultera i en ökad frisättning av fettsyror, hormoner och proinflammatoriska molekyler och uppkomsten av metabolt aktiverad inflammation. LÄS MER

  5. 4. Multi-level multi-scaled metabolites simulation

    Master-uppsats, Linköpings universitet/Institutionen för medicinsk teknik

    Författare :Hao Li; [2016]
    Nyckelord :multi-level; model; simulation; glucose uptake; diabetes;

    Sammanfattning : Diabetes is a world-wide health problem with 415 millions of people suffering from the disease. Most diabetics are suffering from Type 2 Diabetes, which is preceded by insulin resistance in glucose utilizing tissues, such as adipose, liver, and muscle tissues. LÄS MER

  7. 5. Characterization of protein kinase D PKD in the regulation of Drosophila melanogaster homeostasis

    Magister-uppsats, SLU/Dept. of Microbiology

    Författare :Zaid Khan; [2016]
    Nyckelord :protein kinase D; obesity-linked gene; homeostasis;

    Sammanfattning : Insulin signaling is one of the master keys for performing proper regulation of energy metabolism. Serious diseases such as cardiovascular disease, type 2 diabetes and obesity occur due to mis-regulation of insulin pathway. Therefore, it is necessary to recognize the factors that function in the production of insulin and it’s signaling. LÄS MER