Sökning: "integral membrane proteins"

Hittade 5 uppsatser innehållade orden integral membrane proteins.

  1. 1. Optimizing cross-linking to study the interactions between AQP0 and CaM and AQP2 and LIP5

    Master-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Rawya Hussein; [2018]
    Nyckelord :biochemistry; biokemi; Chemistry;

    Sammanfattning : Mammals express thirteen different isoforms of the membrane-bound water channel aquaporin in a tissue-dependent manner. From a medical point of view, two of the most studied isoforms are aquaporin (AQP0), also known as major intrinsic protein and aquaporin 2 (AQP2). LÄS MER

  2. 2. Production of gangliosidebiosynthetic membrane enzymes for biochemical and functionalstudies : Expression, purification and crystallizationoptimization of Thermococcus onnurineus Dolicho l-phosphate mannose synthase, Homosapiens and Branchiostoma floridae Glucosylceramide synthase

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Ellinor Lindholm; [2018]
    Nyckelord :glycoconjugates; glycolipids; integral membrane proteins; gangliosides; glucosylceramide synthase; dolicholphosphate mannose synthase; cancer; neuroblastoma; congenital disorders of glycosylation; glykokonjukat; glykolipider; membranprotein; gangliosider; glukosylceramidsyntas; dolicholfosfat mannossyntas; cancer; neuroblastom; medfdd glykosyleringssjukdom;

    Sammanfattning : Glycolipids play important roles in the biology of prokaryotes and eukaryotes, including humans, and although theyare found on the cell-membrane surface of all eukaryotic cells, not much is known about their biosynthesis. The aim ofthis project was to characterize two enzymes: glucosylceramide synthase (GCS) which is involved in the biosynthesisof glycolipids such as gangliosides that are abundant in the membranes of nerve cells; and dolicholphosphate mannosesynthase (DPMS), involved in the synthesis precursor for protein glycosylation. LÄS MER

  3. 3. Insertion of transmembrane 5-lipoxygenase activating protein (FLAP) into nanodiscs towards structure function studies of complex formation with soluble proteins

    Master-uppsats, SLU/Dept. of Molecular Biology (until 131231)

    Författare :Rampradeep Samiappan; [2013]
    Nyckelord :nanodiscs; 5-lipoxygenase; FLAP;

    Sammanfattning : Leukotrienes are specialized lipid molecules derived from arachidonic acid that have severe pathological roles in inflammatory diseases like asthma, allergy and in the formation of cardiovascular diseases. Since these diseases can be fatal if not treated, it is significant to study leukotriene products and how they form. LÄS MER

  4. 4. Hydrogen production in Escherichia coli : Genetic engineering of the formate hydrogenlyase complex

    Master-uppsats, Institutionen för fysik, kemi och biologi; Tekniska högskolan

    Författare :Charlotte Hjersing; [2011]
    Nyckelord :Escherichia coli; Formate hydrogenlyase; Hydrogenase; Oxygen tolerance;

    Sammanfattning : Biofuels that are renewable and environmentally benign constitute an important area of research, as the supply of fossil fuels decreases and the amount of green house gases in the atmosphere increases. Biohydrogen is not as well explored as other biofuels, but its properties render it a promising complement, as it is clean and can be used directly in fuel cells to generate electricity, the only waste products being water and heat. LÄS MER

  5. 5. An Investigation of the Nano-Organization of Glucose Transporters, Glut1 and Glut3, in the Mammalian Plasma Membrane

    Master-uppsats, Institutionen för vård och natur

    Författare :Dommaraju Sireesha; [2008]
    Nyckelord :Sireesha; Dommaraju; Gluts; Sweden; Denmark; skovde; Odense; skovde University; SDU university;

    Sammanfattning : Glucose is a monosaccharide and fuel for body, it cannot pass through membrane by simple diffusion so, integral transmembrane proteins named glucose transporters (Gluts) are involved in the regulation of the movement of glucose between the extracellular and intracellular spaces within the body. GLUT1 and GLUT3 have previously been shown by cold detergent extraction methods to reside in distinct plasma membrane domains in non-polarized mammalian cells, with GLUT1, but not GLUT3, residing  in detergent-resistant membrane (DRM) domains. LÄS MER