Sökning: "keratin genen mutation"

Hittade 1 uppsats innehållade orden keratin genen mutation.

  1. 1. Generation of mutated expression plasmid KRT1 and comparison of HaCaT cells transfected with expression plasmid KRT1 or KRT10 concerning keratin aggregates

    Kandidat-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Jennifer Eriksson; [2012]
    Nyckelord :Epidermolytic ichtyosis; keratinocytes; keratinfilaments; keratin genen mutation; 4-PBA;

    Sammanfattning : Introduction The genetic skin disease epidermolytic ichtyosis is caused by mutations in either keratin gene 1 or 10 and leads to blisters and hyperkeratosis of the epidermis. At cellular level the disease is seen as aggregates in the keratin filaments. LÄS MER