Sökning: "long-read sequencing"
Visar resultat 1 - 5 av 9 uppsatser innehållade orden long-read sequencing.
1. Methodological development of human telomere sequencing with the Oxford Nanopore Technologies
Magister-uppsats, Örebro universitet/Institutionen för hälsovetenskaperSammanfattning : Human DNA is protected with telomeres, which consist of the repetitive DNA-sequence TTAGGG. A 3’-overhang folds back and in combination with the shelterin complex protects the ends of the DNA. LÄS MER
2. Establishing novel approaches for assessing safety of genome-editing-based therapeutics
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Genome editing based medicines are a new therapeutic modality being developed. They show great promise for a spectrum of genetic diseases lacking conventional treatment strategies. A major obstacle that prevents such therapies to reach the clinic is their safety. LÄS MER
3. Lactobacillus spp. in honey bees of southwestern Sweden : A feasible gut-analysis via long-read 16S nanopore sequencing
Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskapSammanfattning : Together with other pollinating animals, honeybees maintain an ecological stability and pollinate both wild and cultivated plants, contributing to the preservation of natural ecosystems and overall security of food production. Unfortunately, honeybees across the world are dying at a dramatic rate, which is very dangerous for the biosecurity of this planet. LÄS MER
4. Differential expression and function of fubl-1 gene isoforms in C. elegans
Kandidat-uppsats, Uppsala universitet/Molekylärbiologi; Uppsala universitet/Mikrobiologi och immunologi; Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Alternative splicing is the process of producing a variety of transcripts from one and the same gene. This adds further possible variability to gene expression and can in theory mean that one protein coding gene can produce multiple proteins with potentially different functions. LÄS MER
5. Structural variation identification in non-reference cattle breed genomes
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Cattle are essential for the global food industry through the meat and milk production. It is from an economical point of view in our best interest to make cattle as efficient as possible, whether it is milk or beef production, without negatively influencing their health and welfare. LÄS MER
