Sökning: "mRNA-expression"

Visar resultat 1 - 5 av 38 uppsatser innehållade ordet mRNA-expression.

  1. 1. The Quantitative Expression of Transport Proteins SLC38A1-11 in Nerve Cell Development

    Uppsats för yrkesexamina på grundnivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Maryam Dinar; [2023]
    Nyckelord :SLC38A1; SNAT1; SLC38A2; SNAT2; SLC38A3; SNAT3; SLC38A4; SNAT4; SLC38A5; SNAT5; SLC38A6; SNAT6; SLC38A7; SNAT7; SLC38A8; SNAT8; SLC38A9; SNAT9; SLC38A10; SNAT10; SLC38A11; SNAT11; SLC; SLC38; SNATs; SNAT; RT-qPCR; GABA; glutamine; glutamate;

    Sammanfattning : Solute carriers consist of over 400 genes and 66 subfamilies and are the largest group of membrane bound transporters. They facilitate movement of many molecules through cells and organelles and are crucial for upholding many key functions in the human body. They are also involved in the pathophysiology of several diseases. LÄS MER

  3. 2. PAMPaR: Parallel Analysis of miRNAs, Proteins and RNAs. Dynamic Profiles of miRNAs, mRNAs and Specific Proteins in Mouse Embryonic Stem Cells Differentiating into Neural Precursors

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Amelie Carlström; [2023]
    Nyckelord :PAMPaR; SPARC; Proximity extension assay; Neuronal differentiation; Mouse embryonic stem cells; PAMPaR; SPARC; Proximity extension assay; Neuronal differentiering; embryonala musstamceller;

    Sammanfattning : MikroRNA-molekyler (miRNA) är viktiga icke-kodande RNA-molekyler för post-transkriptionell reglering av proteinkodande gener. De har även effekter på många cellulära processer såsom differentiering. De biosyntetiska reaktioner som skapar miRNA involverar proteiner som själva regleras av miRNA. LÄS MER

  4. 3. A study on the association between protein and mRNA expression of skeletal muscle cells and pain manifestations in patients with chronic low back pain

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för integrativ medicinsk biologi (IMB)

    Författare :Dina Hong; [2023]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  5. 4. Phenotype and function of imiquimod-treated MUTZ-3 derived Langerhans cells in potential psoriatic 3D skin model

    Master-uppsats, Malmö universitet/Institutionen för biomedicinsk vetenskap (BMV)

    Författare :Emilie Allentoft Schousboe; [2023]
    Nyckelord :3D models; imiquimod; Langerhans cells; MUTZ-3 cell line; pro-inflammatory cytokines; psoriasis;

    Sammanfattning : Upon encounter of an antigen, epidermis-resident Langerhans cells (LCs) become activated and present the processed antigen to T cells of the draining lymph nodes, resulting in tolerogenic or inflammatory responses. In psoriasis plaques, skin homeostasis is disrupted and replaced by an inflammatory dermatitis. LÄS MER

  7. 5. The role of AmotL2 in the regulation of mesenchymal transitioning of endothelial cells

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Anita-Ann Monteiro; [2023]
    Nyckelord :Endothelial-mesenchymal transition EndMT ; atherosclerosis; transforming growth factor β TGF-β ; Angiomotin-Like 2 AmotL2 ; Scrambled Scr ; knockdown kd ; Immunofluorescence IF ;

    Sammanfattning : Background During development, endothelial cells acquire mesenchymal-like properties to migrate and facilitate normal vascular formation. This process of transformation is known as endothelial to mesenchymal transition (EndMT) and has also been implicated in diseases like vascular pathologies contributing to endothelial inflammation, atherosclerosis and tumour angiogenesis. LÄS MER