Sökning: "metabolic modelling"

Visar resultat 1 - 5 av 9 uppsatser innehållade orden metabolic modelling.

1. 1. Mathematical Modelling Of Cortisol Response To Exercise

   Master-uppsats, Linköpings universitet/Institutionen för medicinsk teknik

   Författare :Arpitha Honnal Venkatesh; [2022]
   Nyckelord :Cortisol; Exercise; Mathematical model; CRH; ACTH; CORT; Cortisol model; HPA axis;

   Sammanfattning : Exercise is widely recognized for its role in the health management and prevention of several chronic diseases. Exercise is considered as a stimulus in the form of physical stress to which a group of anatomical structures in the human body responds by generating a stress response that enables certain physiological modifications essential for restoring systemic homeostasis. LÄS MER

3. 2. Intermediate Biomarkers of Cancer Risk are Altered by DifferentIntensity Levels of Physical Activity in Older AdultsMalin

   Master-uppsats, Örebro universitet/Institutionen för hälsovetenskaper

   Författare :Malin Esbjörnson; [2022]
   Nyckelord :;

   Sammanfattning : AbstractIntroduction: Cancer is the leading cause of death worldwide, and the risk increases as ageincreases. Additionally, chronic inflammation is highly prevalent in older adults, and isassociated with cancer. LÄS MER

4. 3. Intermediate Biomarkers of Cancer Risk are Altered by Different Intensity Levels of Physical Activity in Older Adults

   Master-uppsats, Örebro universitet/Institutionen för hälsovetenskaper

   Författare :Malin Esbjörnson; [2022]
   Nyckelord :Inflammatory markers; systemic inflammation; chronic inflammation; exercise; training;

   Sammanfattning : Introduction: Cancer is the leading cause of death worldwide, and the risk increases as age increases. Additionally, chronic inflammation is highly prevalent in older adults, and is associated with cancer. LÄS MER

5. 4. Metabolic Modelling of Differential Drug Response to Proteasome Inhibitors in Glioblastoma Multiforme

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

   Författare :Clara Bernedal Nordström; [2021]
   Nyckelord :;

   Sammanfattning : This project was built upon a previous study (Johansson et al.2020) that tested multiple drugs on glioblastoma cell lines and found a big division between the drug response for proteasome inhibitors. LÄS MER

7. 5. Reconstruction of Genome-Scale Metabolic Models with Concomitant Constraint-Based Modelling for Flux Prediction – a Case Study of Syngas Consuming Hydrogenophaga pseudoflava

   Master-uppsats, Lunds universitet/Teknisk mikrobiologi

   Författare :Cristopher Ollagnier Widén; [2020]
   Nyckelord :Applied Microbiology; flux-balance analysis FBA ; genome-scale metabolic model GEM ; Hydrogenophaga pseudoflava DSM 1084; KEGG; metabolic engineering; metabolic modelling; metabolic network reconstruction; RAVEN; syngas; systems biology; Technology and Engineering;

   Sammanfattning : Metabolic modelling coupled with flux-balance analysis (FBA) has become a popular tool in systems biology for quantitative predictions of metabolic processes in silico, and as an aid in metabolic engineering. Drawing upon gene-protein-reaction associations deducible from information on the genome-level, so-called genome-scale metabolic models (GEMs) are unequalled in their scope as they attempt to encapsulate the entire reactome of a species or cell type. LÄS MER