Sökning: "neuronal differentiation"

Hittade 4 uppsatser innehållade orden neuronal differentiation.

  1. 1. Sex differences in neuronal differentiation of human stem cells

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Olga Doszyn; [2019]
    Nyckelord :stem cells; neural stem cells; embryonic stem cells; sex differences; neuronal differentiation;

    Sammanfattning : Sexual dimorphism has been long noted in human neurobiology, apparent most notably in sex-biased distribution of multiple neurological disorders or diseases, from autism spectrum disorder to Parkinson's disease. With the advances in molecular biology, genetics and epigenetics have come into focus as key players in sexually dimorphic neural development; and yet, many studies in the field of neuroscience overlook the importance of sex for the human brain. LÄS MER

  2. 2. Evaluating and Optimizing a Protocol for Mesodermal Differentiation of Pluripotent Stem Cells towards Cardiomyocytes and Adipocytes

    H-uppsats, Chalmers tekniska högskola/Institutionen för teknisk fysik

    Författare :Anders Lundin; [2013]
    Nyckelord :Induced pluripotent stem cells; Cardiomyocyte; Adipocyte; Differentiation;

    Sammanfattning : The fat epidemic is an increasing issue in today’s society, and with it follows obesity-related diseases, such as type 2 diabetes and coronary heart disease. Many of today’s drug candidates are withdrawn from the market due to negative cardiac effect, which result in huge setbacks for drug companies if detected at late stage trials Therefore, there is a necessity of appropriate in vitro models, which can detect these toxic effects at early stages in drug development. LÄS MER

  3. 3. Analysis and implementation of anefficient solver for large-scalesimulations of neuronal systems

    Master-uppsats, KTH/Numerisk analys, NA

    Författare :Matthew The; [2013]
    Nyckelord :;

    Sammanfattning : Numerical integration methods exploiting the characteristics of neuronal equation systems were investigated. The main observations was a high stiffness and a quasi-linearity of the system. The latter allowed for decomposition into two smaller systems by using a block diagonal Jacobian approximation. LÄS MER

  4. 4. Electrochemical synthesis of electroactive polymers for drugrelease for bio scaffolds.

    Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Robert Almquist; [2010]
    Nyckelord :Electrochemically Controlled Drug Release; Medical Devices; Conducting Polymers;

    Sammanfattning : Stem cell based therapy has the potential to treat several severe diseases; Parkinson’sdisease is one well- known example. Transplantation of stem cell derived cells intoanimal models is unfortunately often associated with tumour formation or- uncontrolledgrowth of the transplanted cells. LÄS MER