Sökning: "non-coding RNAs"

Visar resultat 1 - 5 av 16 uppsatser innehållade orden non-coding RNAs.

  1. 1. PAMPaR: Parallel Analysis of miRNAs, Proteins and RNAs. Dynamic Profiles of miRNAs, mRNAs and Specific Proteins in Mouse Embryonic Stem Cells Differentiating into Neural Precursors

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Amelie Carlström; [2023]
    Nyckelord :PAMPaR; SPARC; Proximity extension assay; Neuronal differentiation; Mouse embryonic stem cells; PAMPaR; SPARC; Proximity extension assay; Neuronal differentiering; embryonala musstamceller;

    Sammanfattning : MikroRNA-molekyler (miRNA) är viktiga icke-kodande RNA-molekyler för post-transkriptionell reglering av proteinkodande gener. De har även effekter på många cellulära processer såsom differentiering. De biosyntetiska reaktioner som skapar miRNA involverar proteiner som själva regleras av miRNA. LÄS MER

  3. 2. Non-coding RNAs as therapeutic agents : The future of therapy

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Hederoth Gustaf; Lyngå Olivia; Rudqvist Olivia; Jeppsson Rebecka; Hogolof Saida; Svanberg Sara; Kauppinen Veera; [2022]
    Nyckelord :Non-coding RNA; Oligonucleotide therapeutics;

    Sammanfattning : Non-coding RNA (ncRNA) therapeutics are based on short oligonucleotides, both naturally occurring and artificial, which target RNA in a site-specific way to modulate gene expression. As of today, 12 synthetically produced ncRNA-based drugs are available on the market in the US and Europe, and there is a possibility of more to be approved in the near future. LÄS MER

  4. 3. Comprehensive Analysis of lncRNA and circRNA Mediated ceRNA network in Psoriasis

    Magister-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Saima Imran; [2022]
    Nyckelord :;

    Sammanfattning : Evidence is accumulating that noncoding RNAs and circRNA are involved in psoriasis; however, the competing endogenous RNA (ceRNA) mediated regulatory mechanisms in psoriasis are rarely reported. The research study aimed to comprehensively investigate the differences in the expression levels of circular RNA (circRNA), long non-coding RNA (lncRNA), microRNA (miRNA/miR), and mRNA in psoriasis. LÄS MER

  5. 4. Identification and network analysis of candidate microRNA biomarkers in neuroblastoma : A meta-analysis

    Master-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Andreas Svensson; [2022]
    Nyckelord :;

    Sammanfattning : Neuroblastoma constitutes roughly 8% of all childhood cancers where 95% of all neuroblastoma cases occur before the age of 10. The survival rate of infants and young children is very poor, which alone contributes to research novel biomarkers for classification methods, improved diagnosis and better anti-tumor therapies. LÄS MER

  7. 5. Search for the Argonaute protein that governs miRNA regulation in Dictyostelium discoideum

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Miranda Åström; [2021]
    Nyckelord :Argonaute proteins; RNA interference; miRNA; 3xFLAG-tag;

    Sammanfattning : MicroRNAs are small non-coding RNAs that regulate gene expression through RNA interference. These small RNAs enact gene silencing by forming a RNA-inducing silencing complex together with the effector protein Argonaute. The function of the Argonautes in the social amoeba Dictyostelium discoideum is not yet fully understood. LÄS MER