Sökning: "oncolysis"

Hittade 4 uppsatser innehållade ordet oncolysis.

  1. 1. Development of a cell killing adenovirus with a novel cytotoxic transgene

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Carl Blomqvist; [2023]
    Nyckelord :;

    Sammanfattning : Cancer is among the most common causes of human deaths globally. Because of limitations and adverse effects of conventional cancer treatments, the need for new treatments is imminent. LÄS MER

  3. 2. Evaluating LOAd703 in combination with chemotherapeutic agents in ovarian cancer

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Jonas Härdin; [2022]
    Nyckelord :Clinical Immunology; Immunotherapy; LOAd; Ovarian Cancer; Oncology; Virus;

    Sammanfattning : Ovarian cancer is a disease with a high rate of mortality where the need for novel treatments will increase in the near future as older and populous generations reach the age where the cancer is usually diagnosed. Once treated, ovarian cancer tends to recur and display a newfound resistance against the platinum-based chemotherapeutic drugs that are used to treat the disease. LÄS MER

  4. 3. Oncolytic viruses armed with immunostimulatory genes for cancer treatment

    Master-uppsats, Uppsala universitet/Institutionen för immunologi, genetik och patologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Mantas Šilanskas; [2018]
    Nyckelord :Cancer; Virus; Immunotherapy;

    Sammanfattning : Cancer is a major health burden in modern society, costing millions of lives worldwide and negatively impacting many more. With increasing rates of cancer, there is a need for new approaches to its treatment. LÄS MER

  5. 4. Screening of pancreatic cancer cell lines with oncolytic adenovirus Ad5ΔE1ACR2ΔE1B19k (Ad5ΔΔ) in combination with chemotherapeutics

    L3-uppsats, SLU/Dept. of Biomedical Sciences and Veterinary Public Health

    Författare :Cecilia Kallin; [2009]
    Nyckelord :gene therapy; adenovirus; pancreatic cancer; oncolysis; chemotherapy;

    Sammanfattning : Pancreatic cancer is one of the most aggressive and lethal forms of cancer, with high mortality and short survival. Chemotherapy using Gemcitabine is the most common treatment used but tumours frequently show resistance to the drug, necessitating the development of new and more potent therapy options. LÄS MER