Sökning: "oncolytic virus"

Visar resultat 1 - 5 av 9 uppsatser innehållade orden oncolytic virus.

  1. 1. Development of a cell killing adenovirus with a novel cytotoxic transgene

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Carl Blomqvist; [2023]
    Nyckelord :;

    Sammanfattning : Cancer is among the most common causes of human deaths globally. Because of limitations and adverse effects of conventional cancer treatments, the need for new treatments is imminent. LÄS MER

  3. 2. Evaluating LOAd703 in combination with chemotherapeutic agents in ovarian cancer

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Jonas Härdin; [2022]
    Nyckelord :Clinical Immunology; Immunotherapy; LOAd; Ovarian Cancer; Oncology; Virus;

    Sammanfattning : Ovarian cancer is a disease with a high rate of mortality where the need for novel treatments will increase in the near future as older and populous generations reach the age where the cancer is usually diagnosed. Once treated, ovarian cancer tends to recur and display a newfound resistance against the platinum-based chemotherapeutic drugs that are used to treat the disease. LÄS MER

  4. 3. Characterizing the immunogenic cell death induced by Semliki Forest Virus in glioblastoma cell lines

    Master-uppsats, Uppsala universitet/Institutionen för immunologi, genetik och patologi; Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Aishwarya Sivaramakrishnan; [2021]
    Nyckelord :Glioblastoma; Immunogenic Cell Death; Oncolytic Viruses; Semliki Forest Virus; Aishwarya Sivaramakrishnan;

    Sammanfattning : Glioblastoma is the most common primary brain tumor in humans and has a poor prognosis. Current therapies are not curative. Oncolytic viruses (OVs) are being investigated as tools to induce immunogenic cell death (ICD), cell death capable of activating the immune system. LÄS MER

  5. 4. The future of viral vectors for gene therapy

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Elias Ekstedt; Inna Fryckstedt; Hanna Hyllander; Josefin Jonsson; Elin Ring; Felix Wærn; [2021]
    Nyckelord :Gene therapy; adenovirus; alpharetrovirus; baculovirus; adeno-associated virus; lentivirus; herpes simplex virus; foamy virus; gammaretrovirus;

    Sammanfattning : Gene therapy is a fast growing technology that offers treatments for genetic diseases. The method is based on introducing genetic material into a patient to replace the disease-causing gene, using a vector. LÄS MER

  7. 5. Treatment outcomes on malignant gliomas using oncolytic viruses

    Kandidat-uppsats, Uppsala universitet/Institutionen för farmaceutisk biovetenskap

    Författare :Pegah Tehranipour; [2020]
    Nyckelord :oncolytic virus; malignant glioma; reovirus; parvovirus;

    Sammanfattning : Purpose: The objective of this thesis is to evaluate clinical studies that have used oncolytic viruses as treatment and to compare their treatment-outcomes on patients with malignant glioma. Method: This thesis is a systematic literature review where PubMed has been used as the database for data collection. LÄS MER