Sökning: "overexpression"

Visar resultat 1 - 5 av 58 uppsatser innehållade ordet overexpression.

  1. 1. Establishment and Characterisation of new Immunoreagents for diagnosis of Ovarian cancer

    H-uppsats,

    Författare :Fanny Carlsson; [2023-04-19]
    Nyckelord :ovarian; cancer; monoclonal; antibodies; biomarkers; CARM1; PARPi; EZH2i;

    Sammanfattning : Ovarian cancer is the most lethal of all gynaecological cancers and it is often diagnosedat an advanced stage due to diffuse and only mild symptoms at early stages.Early detection is crucial to increase survival but high-grade serous ovarian cancer(HGSOC) often presents non-specific symptoms, such as loss of appetite, bloating ofabdomen and tiredness. LÄS MER

  3. 2. Vilka läkemedelsframsteg har förbättrat prognosen för HER2-positiv metastaserad bröstcancer? : En litteraturstudie

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Helena Hansson; [2023]
    Nyckelord :HER2; Bröstcancer; Läkemedel;

    Sammanfattning : Breast cancer is one of the deadliest forms of cancers in the world. About 15–30% of all breast cancers are HER2-positive, which involves overexpression of HER2-receptors on the surface of tumor cells. LÄS MER

  4. 3. Effects of phosphorylation on the ADP-ribosylation activity of PARP16

    Kandidat-uppsats, Lunds universitet/Kemiska institutionen

    Författare :Virginia Martín Cristóbal; [2023]
    Nyckelord :ADP-ribosylation; Kinases; PARP16; Phosphorylation; UPR biochemistry; Biochemistry; Chemistry;

    Sammanfattning : PARP16/ARTD15 is an intracellular mono-ADP-ribosyltransferase that catalyzes auto- and heteromodification by transfer of a single ADP-ribose moiety. It belongs to the ADP-ribosyltransferase (ART) superfamily. LÄS MER

  5. 4. Novel tools for high-throughput genetic engineering, selection, and screening for improved Biotin production in E. coli cell factories

    Master-uppsats, Lunds universitet/Bioteknik (master); Lunds universitet/Bioteknik (CI)

    Författare :Wibke Vellguth; [2023]
    Nyckelord :biotin; BioB; biotin synthase; oxidative stress; E. coli; biotechnology; Biology and Life Sciences;

    Sammanfattning : Biotin is an essential co-factor in various metabolic processes and is crucial for the growth and maintenance of living organisms. The market need for biotin is multifaceted and driven by its importance in human health, beauty and cosmetics applications, pharmaceuticals, animal nutrition, and other industries. LÄS MER

  7. 5. Hic2 overexpression increase of cell reprogramming efficiency- a computational study

    Kandidat-uppsats, Lunds universitet/Fysiska institutionen; Lunds universitet/Beräkningsbiologi och biologisk fysik - Genomgår omorganisation

    Författare :Paulina Ibek; [2023]
    Nyckelord :Physics and Astronomy;

    Sammanfattning : Since stem cells have many applications in medicine and can be used for treating e.g. cancer and diabetes, finding efficient methods for producing them is a relevant area of research. LÄS MER