Sökning: "peptide"
Visar resultat 1 - 5 av 182 uppsatser innehållade ordet peptide.
1. Expression optimization in Pichia pastoris with Signal Peptide Shuffling and characterization of putative oxygenases and glucose oxidase
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : .... LÄS MER
2. Creating a High-Throughput Workflow for Automated Peptide Characterization using LC-MS
Master-uppsats, Lunds universitet/Centrum för analys och syntesSammanfattning : In the early stage of a drug discovery project, there is a need for efficient methods that can analyse peptides in short time. This includes methods that confirm the peptide’s identity and estimates its relative purity in an efficient and reliable way. LÄS MER
3. Development of a PNA-drug conjugate for pretargeted delivery of cytotoxic drugs
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/TheranosticsSammanfattning : One of the major challenges in cancer treatment is delivering high enough doses of active substance specifically to cancer cells without accumulation in healthy organs. Pretargeting has emerged as a potential solution, where the delivery of a cancer recognizing (primary) agent and a cancer killing (secondary) agent are separated. LÄS MER
4. Understanding the effects of TCP-25 and EDTA interaction : A study of the biophysical aspects of a naturally derived peptide formulation with EDTA for topical application
Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)Sammanfattning : Chronic wounds are an emerging healthcare issue and current methods of healing chronic wounds address bacteria but are ineffective against resistant bacteria and the biofilm formation commonly observed in these wounds. Antimicrobial peptides (AMPs) derived from the endogenous wound healing system have been shown to combat bacterial infections, exhibit immunomodulatory effects, as well as improving wound healing. LÄS MER
5. Design and Evaluation of Peptide Binders : In silico evaluation and comparison of generative AI for de novo peptide binder design
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Beräkningsbiologi och bioinformatikSammanfattning : Peptide binders are short proteins that bind to larger proteins. Due to peptide binders having high specificity and being cheap to synthesize, they are a prime candidate for drug design. Creating new proteins in silico can be divided into three steps: protein backbone generation, sequence design, and computational filtering. LÄS MER