Sökning: "pharmacokinetics"
Visar resultat 1 - 5 av 52 uppsatser innehållade ordet pharmacokinetics.
1. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk kemiSammanfattning : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. LÄS MER
2. Translation of pharmacometric models from NONMEM to nlmixr2 and RxODE2
Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för farmaciSammanfattning : The gold standard for pharmacometrics modeling, along with its modeling format, is currently NONMEM. In order to use other software, there is often a manual step of converting a model from one format to another, which is both time-consuming and causes manual errors. LÄS MER
3. Towards individualised anaesthesia: A comparison between target-controlled infusion and closed-loop control
Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Institutionen för reglerteknikSammanfattning : Individualised healthcare is the future of medicine, due to the so called inter-patient variability. The inter-patient variability involves differences in the drug response between different patients. The effect of a drug can usually be divided into pharmacokinetics (PK) and pharmacodynamics (PD). LÄS MER
4. Tezepelumab : En ny effektiv behandling för patienter med svår, okontrollerad astma?
Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)Sammanfattning : Bakgrund Astma är en kronisk sjukdom som försvårar lungfunktion och påverkar individer hela livet. Orsakerna för astma är olika mellan olika individer, men sjukdomen har liknande symtom. LÄS MER
5. Implementation of a Conceptual Computational Model to estimate the Delay Time in Drug Delivery to reduce Medication Errors in Pediatric Emergency Care
Master-uppsats, KTH/Medicinteknik och hälsosystemSammanfattning : Infusion pumps are used in all departments of a hospital, in the emergency care unit as well as in pediatrics. The pumps administer intravenous medications for the purpose of helping patients to manage pain and are unfortunately not spared from emerging errors. LÄS MER