Sökning: "primary cell cultures"

Visar resultat 1 - 5 av 8 uppsatser innehållade orden primary cell cultures.

  1. 1. Evaluating LOAd703 in combination with chemotherapeutic agents in ovarian cancer

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för immunologi, genetik och patologi

    Författare :Jonas Härdin; [2022]
    Nyckelord :Clinical Immunology; Immunotherapy; LOAd; Ovarian Cancer; Oncology; Virus;

    Sammanfattning : Ovarian cancer is a disease with a high rate of mortality where the need for novel treatments will increase in the near future as older and populous generations reach the age where the cancer is usually diagnosed. Once treated, ovarian cancer tends to recur and display a newfound resistance against the platinum-based chemotherapeutic drugs that are used to treat the disease. LÄS MER

  3. 2. Effect of Ibuprofen on the growth of Pseudokirchneriella subcapitata

    Kandidat-uppsats, Högskolan i Skövde/Institutionen för biovetenskap

    Författare :Mario Flos Berga; [2022]
    Nyckelord :P. subcapitata; toxicity test; contaminants of emerging concern; Ibuprofen;

    Sammanfattning : Pharmaceuticals are an important class of pollutants in aquatic ecosystems. Detected concentration are typically in the range 1 ng/L – 1 μg/L. Traditional wastewater treatment does not provide a complete removal of these contaminants; hence, they may have a negative impact on the environment. LÄS MER

  4. 3. Investigation of immunomodulatory properties of anti-secretory factor in experimental brain tumor models

    Kandidat-uppsats, Lunds universitet/Läkarutbildningen

    Författare :Hanin Fabiana El-Sabee; Amanda Peetre; [2020]
    Nyckelord :Antisecretory factor; Immunomodulation; Glioblastoma; Medicine and Health Sciences;

    Sammanfattning : Introduction: Glioblastoma is the most aggressive form of primary brain tumor in adults. Current treatment including chemotherapy poses a limitation due to consequences of systemic toxicity. Further studies for alternative, multimodal treatments are necessary. Antisecretory factor is an endogenous protein. LÄS MER

  5. 4. Validation of micro-platelet LED for subcellular optogenetic activation in primary cell cultures

    Master-uppsats, Lunds universitet/Fasta tillståndets fysik; Lunds universitet/Fysiska institutionen

    Författare :Daniel Jaghobi Pourshalmani; [2018]
    Nyckelord :Optogenetics; epilepsy; microplatelet; LED; primary cell cultures; adhesion proteins; electrophysiology; Medicine and Health Sciences;

    Sammanfattning : Epilepsy is to this day still a serious neurological diseases where treatments such as pharmaceutical agents and surgery can at most alleviate the symptoms, but not cure it. This disease is still not fully understood at a cellular and network-level, but the recent advancements in the field of optogenetics can serve as an alternative way of studying the brain and diseases such as epilepsy. LÄS MER

  7. 5. Green and red fluorescent protein tagging of endogenous proteins in glioblastoma using the CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 system

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Jenny Lindvall; [2016]
    Nyckelord :Glioblastoma; Cancer stem cells; CRISPR Cas9; Nestin; GFAP; GFP; RFP;

    Sammanfattning : Glioblastoma multiforme is the most malignant primary brain tumor that affects adults, recognized by the World Health Organization as an aggressive grade IV astrocytoma. Patients diagnosed with this type of tumor are left with a poor prognosis even with the most advanced treatment available. LÄS MER