Sökning: "progression-free survival"

Visar resultat 1 - 5 av 10 uppsatser innehållade orden progression-free survival.

  1. 1. Vilka läkemedelsframsteg har förbättrat prognosen för HER2-positiv metastaserad bröstcancer? : En litteraturstudie

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Helena Hansson; [2023]
    Nyckelord :HER2; Bröstcancer; Läkemedel;

    Sammanfattning : Breast cancer is one of the deadliest forms of cancers in the world. About 15–30% of all breast cancers are HER2-positive, which involves overexpression of HER2-receptors on the surface of tumor cells. LÄS MER

  3. 2. Integrating web data miningand machine learningalgorithms to predict progression free survival and overall survival in multiple myeloma patients

    Master-uppsats, Uppsala universitet/Institutionen för informationsteknologi

    Författare :Yijie Zhou; [2023]
    Nyckelord :;

    Sammanfattning : Multiple myeloma patients have highly variable progression free survival and overall survivalranging from a few weeks to more than 5 years. Stratification of these patients can help toidentify high risk patients i-e patients with short-term progression free survival and overallsurvival. LÄS MER

  4. 3. Role of CDK4/CDK6 inhibitors: Ribociclib, Palbocilcib and Abemacilcib in treatment of metastatic breast cancer

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Nazanin Ghobadpour; [2021]
    Nyckelord :Breast cancer; cdk4 6 inhibitors; Bröstcancer; cdk4 6 hämmare;

    Sammanfattning : Breast cancer is the most common cancer among women in Sweden and globally. Socio-demographic, genetic and productive factors together with some endogenous and exogenous hormones and lifestyle are some of the risk factors that can cause this type of cancer. LÄS MER

  5. 4. Differences in tumor volume for treated glioblastoma patients examined with 18F-fluorothymidine PET and contrast-enhanced MRI

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för fysik

    Författare :Karolina Hedman; [2020]
    Nyckelord :PET MRI; positron emission tomography; magnetic resonance imaging; brain tumor; glioblastoma; image segmentation; adaptive thresholding; feature extraction; radiotracer; gadolinium; image processing; image analysis;

    Sammanfattning : Background: Glioblastoma (GBM) is the most common and malignant primary brain tumor. It is a rapidly progressing tumor that infiltrates the adjacent healthy brain tissue and is difficult to treat. Despite modern treatment including surgical resection followed by radiochemotherapy and adjuvant chemotherapy, the outcome remains poor. LÄS MER

  7. 5. Censoring Bias in Oncology Clinical Trials

    Kandidat-uppsats, Lunds universitet/Matematisk statistik

    Författare :Andrea Mattsson; [2020]
    Nyckelord :survival analysis; censoring; progression-free survival; Cox proportional hazards model; oncology clinical trial; HER2CLIMB; Mathematics and Statistics;

    Sammanfattning : Time to disease progression or death (PFS) is of main interest in oncology clinical trials. The data is commonly analyzed using a Cox model. Early discontinuation gives uncertainty in the estimated hazard ratio (HR). Censoring is generally used to handle discontinuations. LÄS MER