Sökning: "protein aggregation"

Visar resultat 1 - 5 av 61 uppsatser innehållade orden protein aggregation.

  1. 1. Effects of mixed surfactant system on chemical and physical stability of human growth hormone

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Karnsinee Viriyayudhakorn; [2023]
    Nyckelord :human growth hormone; surfactant; refolding; protein stability; physical degradation; chemical degradation; pharmaceutical technology; Technology and Engineering;

    Sammanfattning : In protein formulation, addition of surfactants is commonly executed to enhance product stability and shelf-life. The reason is that surfactants can protect proteins against surface-induced aggregation. However, the interaction between surfactant and protein depends on the type of surfactant used. LÄS MER

  3. 2. Properties & Stability of Hybrid Pea-Dairy Protein Formulas

    Master-uppsats, Lunds universitet/Förpackningslogistik

    Författare :Kyriaki-Eirini Moschou; [2023]
    Nyckelord :properties; stability; hybrid formula; pea-dairy; protein mixtures; development; RTD; Agriculture and Food Sciences;

    Sammanfattning : The aim of this study was to investigate the functional properties and stability of hybrid pea-dairy protein formulas. To achieve this goal, the combination of pea protein isolate (PPI) with dairy proteins such as micellar casein isolate (MCI), sodium caseinate (NaCas), whey protein aggregate (WPA) was evaluated. LÄS MER

  4. 3. Methods to study device induced aggregation of proteins

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Marie Therese von Wowern; [2023]
    Nyckelord :protein formulation; protein aggregation; insulin; silicone oil; syringe; shear stress; subvisible particle; size exclusion chromatography; flow imaging microscopy; pharmaceutical technology; Technology and Engineering;

    Sammanfattning : This work developed a method for the investigation of how medical devices, such as syringes and needles, affect the formation of subvisible particles in a protein drug without excipients. Protein-based pharmaceuticals are well known to be sensitive to different kinds of stress, and exposure to stress during the use of this device is unavoidable. LÄS MER

  5. 4. Effect of DNAJB6 on α-synuclein amyloid fibril aggregation and dis-aggregation

    Uppsats för yrkesexamina på avancerad nivå, Lunds universitet/Biofysikalisk kemi

    Författare :Josef Getachew; [2023]
    Nyckelord :α-synuclein; alpha-synuclein; chaperones; DNAJB6; the unhappy chaperone; parkinsons disease; biophysical chemistry; biochemistry; Biology and Life Sciences; Chemistry; Technology and Engineering;

    Sammanfattning : Amyloid proteins are a group of proteins with the ability to form large fibrillar aggregates, identifiable by their cross-β core structure. These aggregates are linked to several different neurodegenerative diseases such as Parkinson’s disease and Alzheimer’s disease and due to the growing rate of people diagnosed, there is a need to combat these diseases. LÄS MER

  7. 5. Characterization of potato protein and its calcium binding capacity

    Master-uppsats, Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

    Författare :Signe König; Erika Thomson; [2023]
    Nyckelord :Patatin; Calcium; Food supplement; Calcium Assay; Alcalase; potato protein; Applied biochemistry; Biology and Life Sciences; Technology and Engineering;

    Sammanfattning : Calcium is essential for the human body as it has functions in the nervous system, bones and formation of teeth. Deficiency in this important nutrient can be detrimental to health and cause life-long issues. Calcium can be found in various foods, like dairy products, but certain plant-based alternatives to milk needs to be fortified with calcium. LÄS MER