Sökning: "protein dynamics"

Visar resultat 1 - 5 av 66 uppsatser innehållade orden protein dynamics.

  1. 1. Transient state UV spectroscopy of Tyrosine and Tyrosine-containing protein

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Hongjian Chen; [2023]
    Nyckelord :Tyrosine; Calmodulin; Autofluorescence; Transient-state monitoring; Electronic state transitions; Tyrosin; Calmodulin; Autofluorescens; Transient-tillståndsövervakning; Elektroniska tillståndsövergångar;

    Sammanfattning : The aromatic amino acids tryptophan, tyrosine, and phenylalanine have been extensively used for different label-free protein studies. These investigations extract information on protein conformations and interactions from the emitted fluorescence's intensity, wavelength, and/or polarization. LÄS MER

  3. 2. Characterization of Antigenic Properties of Two Immunogenic Proteins of Streptococcus pneumoniae 

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Mawj Jasimalsalih; [2023]
    Nyckelord :Immunogenic Proteins; PrsA; MalX; Membrane Vesicles; Protein Properties; Streptococcus pneumoniae virulence factors;

    Sammanfattning : The bacterium Streptococcus pneumoniae (pneumococcus), is considered to be a leading cause of morbidity and mortality globally, particularly in infants and the elderly. It is one of the most frequent causes of respiratory tract infections, which sporadically have the potential to develop into serious invasive symptoms including sepsis and meningitis. LÄS MER

  4. 3. The Stories of Swedish Edible Insects Entrepreneurs : Activities, Business Models, and TIS Evolution

    Master-uppsats, Uppsala universitet/Institutionen för samhällsbyggnad och industriell teknik

    Författare :Chattraporn Chatthong; [2023]
    Nyckelord :sustainable entrepreneurship; entrepreneurial activity; sustainable business model; technological innovation system TIS ; insect entrepreneur; alternative protein; sustainable food;

    Sammanfattning : Sustainability transition has gained more interest in academic research. However, it has rarely been studied specifically from a firm-level perspective. Therefore, this study aims to understand and learn from the firm-level perspective to contribute to firm- and system-level understanding. LÄS MER

  5. 4. Determining Protein Conformational Ensembles by Combining Machine Learning and SAXS

    Master-uppsats, KTH/Tillämpad fysik

    Författare :Samuel Eriksson Lidbrink; [2023]
    Nyckelord :AlphaFold; AlphaFold2; SAXS; protein conformational ensembles; machine learning; protein conformations; reweighting; SAXS; AlphaFold; AlphaFold2; proteinkonformationsensembler; maskininlärning; proteinkonformationer; omviktning;

    Sammanfattning : In structural biology, immense effort has been put into discovering functionally relevant atomic resolution protein structures. Still, most experimental, computational and machine learning-based methods alone struggle to capture all the functionally relevant states of many proteins without very involved and system-specific techniques. LÄS MER

  7. 5. Identifying effects of adrenaline and dopamine binding on the beta2-adrenergic receptor structure and function using machine learning

    Kandidat-uppsats, KTH/Skolan för teknikvetenskap (SCI)

    Författare :Joar Gunnarsson; Leon Bergner; [2023]
    Nyckelord :beta2-adrenergic receptor; GPCR; adrenaline; dopamine; Machine learning; Molecular dynamics simulation;

    Sammanfattning : The beta2-adrenergic receptor is a G-protein coupled receptor, involved in several physiological processes, which enables signaling through the cell membrane. To study the effect of dopamine and adrenaline binding on the receptor structure and function, we used machine learning methods applied to data from molecular dynamics simulations. LÄS MER