Sökning: "protein science"

Visar resultat 1 - 5 av 78 uppsatser innehållade orden protein science.

  1. 1. Development of a novel quantitative PCR analysis method for HIV-1

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Teoretisk kemi

    Författare :Anna-Malin Hallberg; [2021]
    Nyckelord :HIV; PCR; primers; probes; virus; detection; blood plasma; pathogen; biological pharmaceutical; protein-based pharmaceutical; genotype; subtype; RT qPCR; extraction; TaqMa; RNA virus; cross-dimer; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering; Chemistry;

    Sammanfattning : Biological pharmaceuticals are the answer to many severe diseases of today’s society. Some of these are protein-based drugs and can be produced from human blood plasma. In order to guarantee the safety of patients, absence of any pathogens needs to be ensured. LÄS MER

  2. 2. Formulation development of a recombinant VAR2-antiCD3 protein for cancer immunotherapy

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Maja Warlin; Frida Hallberg; [2021]
    Nyckelord :immunotherapy; cancer; pharmaceuticals; proteins; analytical techniques; molecular biotechnology; formulation; life science; engineering; pharmaceutical technology; Technology and Engineering;

    Sammanfattning : The use of immunotherapy for treating cancer has received a lot of attention in the recent years. The therapy is based on activating or deactivating the patient’s own immune system to help fight the disease. One way of doing this, is using bispecific molecules that can target both cancer cells and T-cells simultaneously. LÄS MER

  3. 3. Investigating correlations between chemical connectivity patterns and cancer mutations using machine learning

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för systemteknik

    Författare :Gustav Lind; [2021]
    Nyckelord :;

    Sammanfattning : Proteins are a group of naturally occurring, highly versatile organic macromolecules which can perform a wide range of biological functions in living systems by folding into complex three-dimensional shapes. This thesis project deploys data science and machine learning methods in the study of protein structures with the aim to better the knowledge of the relation between structural and chemical properties of proteins and cancer mutations observed in humans. LÄS MER

  4. 4. IGF-1 hos häst : analysmetodik och träningseffekter

    Kandidat-uppsats, SLU/Dept. of Anatomy, Physiology and Biochemistry

    Författare :Amanda Segervall; [2020]
    Nyckelord :equine; häst; IGF-1; träning;

    Sammanfattning : Hästsporten i Sverige är stor och vi är konkurrenskraftiga i internationella tävlingar. En viktig faktor som påverkas av både fysisk aktivitet, energi- och proteintillförsel är insulin growth factor-1 (IGF1) som är ett hormon som bland annat stimulerar ben- och muskeltillväxt. LÄS MER

  5. 5. Optimizing signal peptides for expression of recombinant antibodies in HEK293 cells

    Master-uppsats, Linköpings universitet/Institutionen för fysik, kemi och biologi

    Författare :Gustav Myhrinder; [2020]
    Nyckelord :Signal peptide; antibody; mammalian cell; HEK293; secretory pathway;

    Sammanfattning : Monoclonal antibodies are well-established as a therapeutic in the biopharmaceutical market, targeting a variety of diseases and with 79 approved products by the United States Food and Drug Administration in December 2019. Therapeutic monoclonal antibodies are commonly produced as recombinant proteins in mammalian cell lines, due to their capacity of post-translational modifications, most notably glycosylation. LÄS MER