Sökning: "range profiling"

Visar resultat 1 - 5 av 29 uppsatser innehållade orden range profiling.

  1. 1. Creating a High-Throughput Workflow for Automated Peptide Characterization using LC-MS

    Master-uppsats, Lunds universitet/Centrum för analys och syntes

    Författare :Sara Forsberg; [2023]
    Nyckelord :High-throughput analysis; Impurity profiling; UHPLC-HRMS; Peptide characterization; Peptide descriptors; Analytical chemistry; Technology and Engineering;

    Sammanfattning : In the early stage of a drug discovery project, there is a need for efficient methods that can analyse peptides in short time. This includes methods that confirm the peptide’s identity and estimates its relative purity in an efficient and reliable way. LÄS MER

  3. 2. Multi-Data Approach for Subsurface Imaging: Combining Borehole and GPR- Data for Improved Analysis

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för fysik

    Författare :Pontus Yngvesson; [2023]
    Nyckelord :Geofysik; Geoteknik; GPR; Borrhål; Dataanalys; Markradar;

    Sammanfattning : The investigation to understand the subsurface and its features has long been asubject of interest for various fields, including fields such as archaeology and infras-tructure projects. However, traditional excavation methods are often costly and time-consuming. LÄS MER

  4. 3. Holistic embedding of equivalent conicity in wheelset maintenance

    Master-uppsats, KTH/Väg- och spårfordon samt konceptuell fordonsdesign

    Författare :Philipp Linzbichler; [2023]
    Nyckelord :Railway Operation; Equivalent Conicity; Wheelset Maintenance; Smart Maintenance; Data Analysis; Järnvägsdrift; Ekvivalent Konicitet; Hjulset Underhåll; Smart Underhåll; Dataanalys;

    Sammanfattning : With continuing digitization of railways an increasing number of data is recorded but particularly in operation advanced analysis tends to be partially rudimentary. Yet, it is essential to implement sophisticated processing for all records in order to develop more purposeful and predictive vehicle maintenance strategies that adhere to the increasing requirements imposed by the homologation. LÄS MER

  5. 4. Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics

    Master-uppsats, Lunds universitet/Institutionen för immunteknologi

    Författare :Johan Thorsson; [2023]
    Nyckelord :Biology and Life Sciences;

    Sammanfattning : Survival for non-small cell lung cancer (NSCLC) patients has been significantly improved by epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with EGFR mutations. However, certain subpopulations of NSCLC patients with EGFR wild-type (wt) status have been shown to also respond to EGFR-TKIs. LÄS MER

  7. 5. Characterization of ulvan polysaccharide degrading enzymes from Wenyingzhuangia fucanilytica

    Master-uppsats, Lunds universitet/Bioteknik; Lunds universitet/Bioteknik (master)

    Författare :Erik Apelqvist; [2022]
    Nyckelord :Enzyme; Enzymatic characterization; Recombinant protein producaiton; Protien purification; E. coli; W. fucanilytica; Transformation; Overexpression; Seaweed; Ulvan; Polysaccharides; biotechnology; Biology and Life Sciences;

    Sammanfattning : The aim of this thesis was to fully characterize the enzyme WFp-105, including bioinformatic analysis, structural modeling, full activity and stability characterization and product determination. As well as for the enzyme WFp-37; optimize protein production in regard to expression strains and cultivation temperature, analyzing the genomic context as well as performing an initial activity detection. LÄS MER