Sökning: "recombinant proteins"

Visar resultat 1 - 5 av 54 uppsatser innehållade orden recombinant proteins.

  1. 1. OPTIMIZATION OF CLONE SELECTION PLATFORM FOR PRODUCTION OF RECOMBINANT PROTEINS

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Basel Yousef; [2024]
    Nyckelord :;

    Sammanfattning : Background  Biologics are type of proteins that can be produced by expression in a foreign host for medical healthcare applications in humans. Monoclonal antibodies (mAbs) are type of biologics that are designed to specifically bind to one target, with a purpose to inhibit a certain molecule that could be associated with a disease process. LÄS MER

  3. 2. The production of recombinant 6LZE_A and NS2B-NS3 in E. coli

    Master-uppsats, Lunds universitet/Bioteknik (master); Lunds universitet/Bioteknik (CI)

    Författare :Raluca Svensson; [2024]
    Nyckelord :coronavirus; dengue; protease; pandemic; SARS-Cov-2; DENV; viral replication; proteins; Escherichia coli; DL-BAPNA; computational modeling; recombinant protein production; biotechnology; Biology and Life Sciences;

    Sammanfattning : Even though the first coronavirus pandemic was registered in 1965, SARS-CoV-2 was better acknowledged when it caused the worldwide pandemic in 2019 in which millions of individuals lost their lives. Due to its facile way of spreading from one individual to another, the number of infected cases has gone up to more than 750 million to this day. LÄS MER

  4. 3. Sortase A coupling of the recombinant partial silk proteins 4Rep-Srt and G-/G5-CT to understand the structure of silk fiber

    Master-uppsats, KTH/Proteinvetenskap

    Författare :Ellen Adlerz; [2023]
    Nyckelord :4RepCT; 4Rep-Srt; G- G5-CT; Sortase A coupling; recombinant silk protein; 4RepCT; 4Rep-Srt; G- G5-CT; Sortase A-koppling; rekombinant silkesprotein;

    Sammanfattning : Spindelsilke är ett intressant material på grund av dess biokompatibilitet och därav användning som biomaterial. Det är jämförbart med konstgjorda material när det gäller styrka och elasticitet, och i kombination med biokompatibiliteten, är spindelsilke eftertraktat inom det medicinska området. LÄS MER

  5. 4. Recombinant expression and purification of sugar beet Phytoglobins in Escherichia Coli BL21 (DE3) including metabolic engineering of the heme biosynthesis

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Pennie Lindblom; Olivia Geel; [2023]
    Nyckelord :Phytoglobin; Heme; δ-ALA; qPCR; SDS-PAGE; Bacterial cultivation; Escherichia coli; BvPgb1.2; ÄKTA; Applied biochemistry; Biology and Life Sciences;

    Sammanfattning : The protein hemoglobin (Hb) is vital for us humans to ensure enough oxygen replacement in the body. Hb-resembling proteins also exist in plants, these are called phytoglobins (Pgbs). Pgbs are very interesting since they can play a considerable role in the development of blood substitutes and iron supplements for human use. LÄS MER

  7. 5. Production, in vitro modification, and interaction analysis of a hydroxyproline-dependent protein

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Biokemi

    Författare :Milica Plavsic; [2023]
    Nyckelord :protein production optimisation; recombinant expression; bioreactor; prolyl hydroxylase; liquid chromatography mass spectrometry; microscale thermophoresis;

    Sammanfattning : The development of a biologic protein involves different stages and becomes a highly complex process which can be costly and time consuming to scale up for industrial production. Therefore, optimization is a necessary part of the production process development to lower the production expenses. LÄS MER