Sökning: "ribosome"
Visar resultat 1 - 5 av 12 uppsatser innehållade ordet ribosome.
1. Understanding the pathophysiology ofrecurrent UBTF mutations associated withpediatric AML
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Acute myeloid leukaemia (AML) is highly heterogeneous haematological malignancy, which represents a challenge in the understanding of the disease. Relapse in AML is common, andmany relapsed patients respond poorly to conventional treatment, leading to a low survivalrate. LÄS MER
2. 3′-end fluorescence labelling of long RNAs using terminal deoxynucleotidyl transferase
Kandidat-uppsats, Lunds universitet/Kemiska institutionenSammanfattning : Through recent years, RNA has rapidly gone from mainly being known as a passive information-carrying molecule within the central dogma of molecular biology to becoming the active ingredient in multiple therapeutics, such as in vaccines and potential drugs against cancer. However, one of the main challenges with RNA as a therapeutic is efficient delivery to cells. LÄS MER
3. Characterization of the role of RbfA and KsgA in ribosome function
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Ribosome biogenesis is the maturation and accurate assembly of ribosomal RNA and proteins to form functional ribosomes competent to enter the translation cycle, facilitated by the action of ribosome biogenesis factors. RbfA and KsgA are two factors involved in late stages of the 30S subunit biogenesis, yet before translation initiation. LÄS MER
4. Translation inhibition in Mycobacterium smegmatis by tuberactinomycins
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildningSammanfattning : Tuberculosis continues to be a global health threat as multiple drug-resistant tuberculosis and extensively drug-resistant tuberculosis become increasingly rampant. Tuberactinomycins, specifically capreomycin, administered in combination with other medicines, remains one of the effective strategies against these deadly strains of tuberculosis. LÄS MER
5. Fidelity of protein synthesis using sequence reconstructed ancient Elongation Factor Tu
Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för cell- och molekylärbiologiSammanfattning : To maintain a healthy growth rate of living cells, protein synthesis must take place accurately and efficiently. Translation, the core step decoding the genetic information, governs both fidelity and efficiency. LÄS MER