Sökning: "semi-mechanistic models"

Hittade 1 uppsats innehållade orden semi-mechanistic models.

  1. 1. Predictability and performance of different non-linear mixed-effects models for HbA1c in patients with type 2 diabetes mellitus

    Master-uppsats, Institutionen för farmaceutisk biovetenskap; Institutionen för biologisk grundutbildning

    Författare :Gustaf Wellhagen; [2014]
    Nyckelord :Type 2 diabetes mellitus; semi-mechanistic models; HbA1c; glucose; insulin; NONMEM;

    Sammanfattning : To accurately predict the outcome of a late phase study, pharmacometric models can help in drug development. Making informed decision on which models to use will also facilitate drug development. This can depend on the mechanism of action for the drug as well as stability and runtime factors. LÄS MER