Sökning: "simulation of chromatography"

Visar resultat 1 - 5 av 16 uppsatser innehållade orden simulation of chromatography.

  1. 1. Orbit-simulator for downstream processes

    Master-uppsats, Lunds universitet/Kemiteknik (CI)

    Författare :Andreas Malmström; [2022]
    Nyckelord :Chemical engineering; Process simulation; Downstream processes; Orbit; Preparative chromatography; Python; Lumped Rate Models; Technology and Engineering;

    Sammanfattning : In an ever more digitilized society, the transition is palpable also in the pharmaceutical industry. The control system Orbit was developed at the department of chemical engineering at Lund University, to be able to automate downstream processes based on the ÄKTA-system. LÄS MER

  2. 2. Simulation of periodic counter-current chromatography purification of monoclonal antibodies with column degradation

    Master-uppsats, Lunds universitet/Kemiteknik (CI)

    Författare :Erik Friberg; [2022]
    Nyckelord :Counter-current chromatography; PCC; Monoclonal antibodies; Affinity chromatography; Process control; Chemical engineering; Process simulation; Chemistry;

    Sammanfattning : The purification process of monoclonal antibodies (mAbs) for therapeutic drugs is expensive, especially the chromatography step in which the mAbs are separated from other proteins and cells present in the feed. The antibodies are separated from the feed using affinity chromatography, where only the antibodies interact with active sites within the column, whereas the rest passes through the column without stopping. LÄS MER

  3. 3. Modeling and simulation of chromatographic separation in Modelon Impact

    Master-uppsats, Lunds universitet/Kemiteknik (CI)

    Författare :Oliver Thelander; [2022]
    Nyckelord :Chemical engineering; Simulering; Modellering; Kromatografi; Adsorption; Modelica; Modelon Impact; Recirkulation; Simulation; Modeling; Chromatography; Recirculation; Technology and Engineering;

    Sammanfattning : The aim of this master thesis is to implement a previously modeled chromatographic adsorp-tion process from MatLab into the Modelon Impact, a simulation software. Modelon Impact is using Modelica as language syntax that is useful for creating a large system of interconnected models that has the potential to work in different configurations. LÄS MER

  4. 4. Discontinuous Galerkin Method for Liquid Chromatography Modelling

    Uppsats för yrkesexamina på avancerad nivå, Umeå universitet/Institutionen för fysik

    Författare :Sara Culligan; [2022]
    Nyckelord :;

    Sammanfattning : Chromatography is a separation technique used predominantly by the medical industry in purification and extraction of components in a solution. The setup is a column filled with resin particles where a solution of two components is filtered and separated due to different rates of interaction with the resin particles. LÄS MER

  5. 5. Simulation Testbed for Liquid Chromatography

    Master-uppsats, Umeå universitet/Institutionen för fysik

    Författare :David Andersson; [2021]
    Nyckelord :;

    Sammanfattning : The stlc package is proposed as a tool for simulation of liquid chromatography by implementing several lumped kinetic models which combine diffusive mass  transport and adsorption isotherm equations. The purpose of the package is to provide computationally efficient approximations to the general rate model of chromatography. LÄS MER