Sökning: "single cell genomics"

Hittade 5 uppsatser innehållade orden single cell genomics.

  1. 1. Regulatory Driven Clustering of Single-Cell Data; Clustering of single-cell RNA sequencing from glioblastoma with a novel mathematical method

    Master-uppsats, Göteborgs universitet/Institutionen för matematiska vetenskaper

    Författare :Kári Kristjánsson; [2023-08-08]
    Nyckelord :;

    Sammanfattning : Cancer is a leading cause of death worldwide. Single-cell RNA sequencing has arisen as an important method to explore the gene expression of biological cells, including cancer cells. In this study, we deployed a computational algorithm known as ScRegClust to dissect single-cell RNA-sequencing (scRNA-seq) data from brain tumors. LÄS MER

  3. 2. Image-Based Classification Solutions for Robust Automated Molecular Biology Labs

    Master-uppsats, KTH/Medicinteknik och hälsosystem

    Författare :Arnold Teo; [2023]
    Nyckelord :Neural networks; Deep learning; Transfer learning; TensorFlow; Single-cell genomics; Image classification; Neurala nätverk; Djupinlärning; Överförd inlärning; TensorFlow; Enskild cellgenomik; Bildklassificering;

    Sammanfattning : Single-cell genomics (SCG) are methods for investigating heterogeneity between biological cells, among these is Smart-seq which sequences from RNA molecules. A more recent version of this method is Smart-seq3xpress which is currently in the process of being automated by the Sandberg lab at Karolinska Institutet. LÄS MER

  4. 3. Single-cell RNA-seq mapping of chicken leukocytes : An investigation into single-cell transcriptomics as an alternative to traditional immunological methods within non-traditional model organisms

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Mikrobiologi och immunologi

    Författare :Matilda Maxwell; [2023]
    Nyckelord :Bioinformatics; scRNA-seq; avian; immunology; Seurat; leukocytes; chicken; gallus gallus; 10x genomics; PCA;

    Sammanfattning : The immune system is a complex infrastructure where many cells interact with each other and perform duties depending on their type and function. When using traditional immunological methods in studying non-traditional model organisms, such as birds, challenges arise. LÄS MER

  5. 4. The role of RFX-target genes in neurodevelopmental and psychiatric disorders

    Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Abhishekapriya Ganesan; [2021]
    Nyckelord :;

    Sammanfattning : Neurodevelopmental disorders such as autism spectrum disorder (ASD) and psychiatric disorders, for example, schizophrenia (SCZ) represent a large spectrum of disorders that manifest through cognitive and behavioural problems. ASD and SCZ are both highly heritable, and some phenotypic similarities between ASD and SCZ have sparked an interest in understanding their genetic commonalities. LÄS MER

  7. 5. Mot en effektiv data- och informationshantering på SiCell

    Kandidat-uppsats, Institutionen för biologisk grundutbildning

    Författare :Ebba Bergman; Viktor Blomkvist; Julia Erkers; Niklas Handin; Joakim Hellner; Jessica Nettelblad; [2013]
    Nyckelord :LIMS; SCG; single cell genomics; SiCell; LIMS; enkelcellsgenomik; enkelcellgenomik; SiCell;

    Sammanfattning : Denna projektrapport är avsedd att vara ett hjälpmedel för SiCell, en del av SciLifeLab Uppsala som ska bli Europas första plattform för enkelcellgenomik till hösten 2013. SiCell har bett projektgruppen om undersökningar gällande ett Laboratory Information Management System, LIMS. På svenska ett datahanteringsystem för laboratorier. LÄS MER