Sökning: "sodium dodecyl sulfate"

Visar resultat 1 - 5 av 11 uppsatser innehållade orden sodium dodecyl sulfate.

  1. 1. Effects of mixed surfactant system on chemical and physical stability of human growth hormone

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Karnsinee Viriyayudhakorn; [2023]
    Nyckelord :human growth hormone; surfactant; refolding; protein stability; physical degradation; chemical degradation; pharmaceutical technology; Technology and Engineering;

    Sammanfattning : In protein formulation, addition of surfactants is commonly executed to enhance product stability and shelf-life. The reason is that surfactants can protect proteins against surface-induced aggregation. However, the interaction between surfactant and protein depends on the type of surfactant used. LÄS MER

  2. 2. Influence of Peristaltic Pump Tubes on Protein Particles Formation for Lipase Enzyme Therapeutic Protein

    Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

    Författare :Salah Elden Omer; [2023]
    Nyckelord :Dynamic Image analysis; Protein aggregation; Peristaltic pump tubing; Particle characterization; PVC tubing; Silicone tubing; Surfactant; QICPIC; Pharmaceutical technology; Biology and Life Sciences;

    Sammanfattning : Introduction: In Bio-pharmaceutical production, peristaltic pump tubing is considered one of the factors that influence protein aggregation. Background: Protein particles present challenges for the control and analysis of various manufacturing processes in the biopharmaceutical industry for their significant effects on safety and quality. LÄS MER

  3. 3. Flödescytometrisk undersökning av inbindning mellan designade topdomänen från transferrinreceptorn till virala glykoproteiner för potentiell användning inom läkemedelsframtagning

    Kandidat-uppsats, Linnéuniversitetet/Institutionen för kemi och biomedicin (KOB)

    Författare :Emma Rydell; [2022]
    Nyckelord :Transferrin receptor; recombinant DNA techniques; protein purification; yeast surface display; flow cytometry; Transferrinreceptor; rekombinant genteknik; proteinupprening; yeast surface display; flödescytometri;

    Sammanfattning : Machupovirus är ett virus som kan orsaka hemorragisk feber hos människor. Efter utvärdering av bindning mellan designade proteiner och virala glykoproteiner skulle proteinerna potentiellt kunna användas vid framtagning av ett proteinbasserat läkemedel mot hemorragisk feber. LÄS MER

  4. 4. PREPARATION AND CHARACTERIZATION OF BOVINE MEAT AND MILK FACTOR VESICLES/PARTICLES & IDENTIFICATION OF MSBI1 REP INTERACTING PROTEINS

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Farhana Manzoor; [2020]
    Nyckelord :Bovine meat and milk factors; multiple sclerosis; immunoprecipitation co-immunoprecipitation; protein dimers; mass spectrometry; immunodetection; cesium chloride density gradient centrifugation; sodium dodecyl sulfate-polyacrylamide gel electrophoresis; vesicle; particle; interaction partner; pull-down assay.;

    Sammanfattning : Introduction: Bovine meat and milk factors (BMMF) frequently isolated from bovine meat and milk, are discussed as putative causative agents for breast, colon and possibly other cancers. The hypothesis was formulated based on earlier correlative studies indicating that BMMFs could indirectly trigger inflammation, accumulate mutational events via reactive oxygen and nitrogen species production which eventually provokes tumor formation. LÄS MER

  5. 5. The influence of molecular structure of phospholipids on the transition from micelles to bilayers in bile salt surfactant/phospholipid mixtures

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för läkemedelskemi

    Författare :Zeyneb Alkademi; [2020]
    Nyckelord :phospholipids; micelles; bilayers; bile salt; surfactant;

    Sammanfattning : Phospholipid molecules self-assemble to form bilayers that are poorly soluble in an aqueous solvent. Phospholipids may, however, be readily dissolved by mixing with a bile salt or amphiphilic drug surfactant that forms mixed surfactant/phospholipid micelles. LÄS MER