Sökning: "synthesized peptides"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden synthesized peptides.

  1. 1. Novel ways of treating bacterial skin infections: the antimicrobial peptides REI-26 and CD4-PP

    Master-uppsats, Uppsala universitet/Institutionen för medicinsk biokemi och mikrobiologi

    Författare :Magdalena de Arriba Sánchez de la Campa; [2022]
    Nyckelord :Antimicrobial peptides; skin infections; wound healing;

    Sammanfattning : Severe skin and soft-tissue infections can lead to septic shock and organ failure. Antibiotic treatment is turning ineffective due to the rise of antimicrobial resistance. This calls for the need for novel antimicrobial therapies such as antimicrobial peptides. LÄS MER

  3. 2. Synthesis of bioactive compounds: Synthetic study of D-Lac-terminated peptidoglycan fragment structures

    Master-uppsats, KTH/Kemiteknik

    Författare :Yu Saito; [2021]
    Nyckelord :organic synthesis; peptidoglycan; lactate; glycopeptide; solid-phase peptide synthesis; organisk syntes; peptidoglycan; laktat; glykopeptid; fastfas-peptidsyntes;

    Sammanfattning : Peptidoglycan (PGN) är en bakteriecellväggskomponent och känd för att känna igen olika receptorer eller enzymer för att leda aktiveringsimmunsystemet. Den allmänna strukturen för PGN består av sockerkedjor inklusive N-acetylglutamin (GlcNAc), N-acetylmuraminsyra (MurNAc) och tvärbundna peptidkedjor. LÄS MER

  4. 3. The synthesis and analysis of a bombesin analogue for radiotherapy of prostate cancer

    Master-uppsats, KTH/Skolan för kemi, bioteknologi och hälsa (CBH)

    Författare :Ábel Nagy; [2019]
    Nyckelord :Prostate cancer; radionuclide therapy; bombesin; gastrin-releasing peptide receptor; albumin binding domain; SPPS; RM26 analogue;

    Sammanfattning : Targeted radionuclide therapy is becoming a widely used cancer treatment strategy. By radiolabeling receptor-specific peptides, cancer cells overexpressing the receptor can be selectively targeted, and the cytotoxic radionuclide can be delivered to the target cell or tissue for therapeutic or diagnostic purposes. LÄS MER

  5. 4. Bioconjugation of RGD peptides on injectable PEGDMA for enhancing biocompatibility

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Polymerkemi

    Författare :Victor Thorendal; [2019]
    Nyckelord :Biocompatibility; Bioconjugation; RGD; Polyethylene glycol dimethacrylate PEGDMA ; Photopolymerization; Surface cell adhesion; Injectable; Dynamic cell culture system;

    Sammanfattning : A cerebral aneurysm is a weakened area of an artery in the brain, creating an abnormal expansion. Recent research for treatment is utilizing a photopolymerizable hydrogel as a possible operation for injection in situ. LÄS MER

  7. 5. Dissecting the Structure-Activity Relationship of Hairpinin, a Plant Derived Antimicrobial Peptide

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Avdelningen för farmakognosi

    Författare :Mia Sterby; [2014]
    Nyckelord :Hairpinin; AMP; peptide; pharmacognosy;

    Sammanfattning : Antibiotic resistance is a growing health issue that necessitates development of alternative drugs with antimicrobial properties. Antimicrobial peptides are a promising group of compounds in this respect and are used by all varieties of living organisms to defend against invading or competing organisms. LÄS MER