Sökning: "tillämpad biokemi"

Visar resultat 6 - 10 av 48 uppsatser innehållade orden tillämpad biokemi.

  1. 6. Structure-based design of new antiviral substances against the Venezuelan equine encephalitis virus

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Elin Öberg; [2022]
    Nyckelord :x-ray crystallography; protein crystallization; Venezuelan equine encephalitis virus; structure-based drug design; applied biochemistry; Technology and Engineering;

    Sammanfattning : The Venezuelan equine encephalitis virus (VEEV) is a highly infectious alphavirus responsible for severe outbreaks and epidemics in the Americas. The nonstructural protein 2 (nsP2) cysteine protease plays a fundamental role in the VEEV replication process, and is therefore, an attractive drug target for structure-based drug design using x-ray crystallography. LÄS MER

  3. 7. Development of a novel quantitative PCR analysis method for HIV-1

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Anna-Malin Hallberg; [2021]
    Nyckelord :HIV; PCR; primers; probes; virus; detection; blood plasma; pathogen; biological pharmaceutical; protein-based pharmaceutical; genotype; subtype; RT qPCR; extraction; TaqMa; RNA virus; cross-dimer; applied biochemistry; tillämpad biokemi; Biology and Life Sciences; Technology and Engineering; Chemistry;

    Sammanfattning : Biological pharmaceuticals are the answer to many severe diseases of today’s society. Some of these are protein-based drugs and can be produced from human blood plasma. In order to guarantee the safety of patients, absence of any pathogens needs to be ensured. LÄS MER

  4. 8. Designing the Superplant: Increasing Lipid Signaling for Enhanced Phosphorus Uptake

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Louise Jedemark; [2021]
    Nyckelord :Lipid flippases; Arabidopsis; Yeast; Transport biology; Applied Biochemistry; Tillämpad biokemi; Biology and Life Sciences; Technology and Engineering;

    Sammanfattning : Phosphate is fundamental for optimal growth and reproduction for plants. However, due to low solubility, not all phosphorus in the soil is available to the plant. It has recently been discovered that plants can take up complex phosphate-containing organic compounds, such as phospholipids. LÄS MER

  5. 9. Development of a reporter gene assay on an automated platform

    Master-uppsats, Lunds universitet/Beräkningskemi; Lunds universitet/Tillämpad biokemi

    Författare :Fanny Redin; [2021]
    Nyckelord :Reporter gene assay; Automation; Svar Life Science; Immunogenicity; TNF-alpha; Applied biochemistry; Technology and Engineering; Biology and Life Sciences;

    Sammanfattning : Biological drugs have the potential to trigger unwanted immunogenic responses in patients which might affect the efficacy and safety of the treatment. Evaluating the immunogenicity throughout the drug development process is therefore crucial. LÄS MER

  7. 10. Whole-Cell Patch Clamp Investigations on Rapid Synaptic Scaling of Mouse CA1 Pyramidal Neurons under Optogenetic Stimulation

    Master-uppsats, Lunds universitet/Tillämpad biokemi; Lunds universitet/Beräkningskemi

    Författare :Leonard Groth; [2021]
    Nyckelord :Patch clamp; Electrophysiology; Optogenetics; Epilepsy; Voltage clamp; Current clamp; Neuroscience; Applied Biochemistry; Tillämpad biokemi; Technology and Engineering;

    Sammanfattning : The brain consists of billions of neurons forming intricate contiguous networks. The connective strength in these networks change throughout life in response to experience and environmental stimuli. LÄS MER