Sökning: "toxicity"

Visar resultat 1 - 5 av 393 uppsatser innehållade ordet toxicity.

  1. 1. Hormonal Influence on the Proliferation Potential of C17.2 Neuronal Progenitor Cells

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Alexander Mangano; [2024]
    Nyckelord :;

    Sammanfattning : The brain is arguably the most complex organ of the body: Controlling muscles, maintaining homeostasis, processing information. It has the longest developmental period of any organ, and hormones are essential during its development. LÄS MER

  2. 2. Synchronization of the circadian rhythm in a cell line used for testing neurodevelopmental toxicity.

    Kandidat-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning

    Författare :Anna Herbert; [2024]
    Nyckelord :;

    Sammanfattning : .... LÄS MER

  3. 3. Quantification of Pharmaceuticals at the sub-cellular level using the NanoSIMS

    Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Analytisk kemi

    Författare :Maryam Dost; [2024]
    Nyckelord :Mass spectroscopy imaging; AstraZeneca; Nanosims; Therapeutics; pharmacokinetics; pharmacodynamics; Quantitative Visualization; calibration curve; RSF; pharmacology; Data Analysis; Chemistry; Quantification; isotopes; Pharmaceuticals; subcellular; drug; drug target; nucleotide; biodistribution; Bioanalytical electrochemistry; spectroscopy; mass spectrometry; analytical separations; Analytical Chemistry; ROI; Bioanalytical Chemistry; Masspektroskopi avbildning; AstraZeneca; Nanosims; Terapeutik; farmakokinetik; farmakodynamik; Kvantitativ visualisering; kalibreringskurva; RSF; farmakologi; Dataanalys; Kemi; Kvantifiering; isotoper; Läkemedel; subcellulär; läkemedel; läkemedelsmål; bioskopisk elektrofördelning; nukleotid; bioskopisk bioskopisk distribution; masspektrometri; analytiska separationer; analytisk kemi; bioanalytisk kemi;

    Sammanfattning : Mass spectroscopy imaging (MSI) has become a vital tool in modern research due to its ability to visualize the spatial distribution of molecules within tissue samples. The collaboration between researchers at AZ, the University of Gothenburg, and Chalmers University of Technology using the NanoSIMS instrument and MSI-SIMS technology has opened up new avenues of exploration in pharmaceutical development, particularly in examining drugs and metabolites at sub-cellular levels. LÄS MER

  4. 4. TOXICITY DRIVERS IN CHEMICAL MIXTURES FROM THE SWEDISH WEST COAST – EFFECTS ON PELAGIC COMMUNITIES

    Master-uppsats, Göteborgs universitet / Institutionen för biologi och miljövetenskap

    Författare :Helena Hartmann; [2023-06-26]
    Nyckelord :;

    Sammanfattning : Human society benefits from a range of ecosystem services provided by the oceans, such as oxygen production, carbon storage, and fishing. However, these services are relying on the ecosystem’s functional and structural integrity, which are correlated to its biodiversity. LÄS MER

  5. 5. ASSESSING MICROBIAL COMMUNITY RESPONSES IN A CHEMICALLY STRESSED FRESHWATER ECOSYSTEM USING ENVIRONMENTAL DNA

    Master-uppsats, Göteborgs universitet / Institutionen för biologi och miljövetenskap

    Författare :Nicolai Laufer; [2023-06-21]
    Nyckelord :;

    Sammanfattning : Microbial communities represent the fundamental cornerstones of riverine ecosystems because they are involved in numerous processes which mediate ecosystem services. However, riverine ecosystems are currently massively altered by a variety of anthropogenic activities which includes changes in landuse and chemical pollution. LÄS MER