Sökning: "trypsin inhibitor"

Visar resultat 1 - 5 av 6 uppsatser innehållade orden trypsin inhibitor.

1. 1. Aromatic Ring Flips and Local Volume Fluctuations in BPTI

   Master-uppsats, Lunds universitet/Biofysikalisk kemi

   Författare :Simon Enbom; [2022]
   Nyckelord :Biophysical Chemistry; Molecular Dynamics; Protein Dynamics; Activation Volume; Aromatic Ring Flips; BPTI; Biology and Life Sciences; Chemistry; Technology and Engineering;

   Sammanfattning : Aromatic ring flips are a classic example of a dynamic process in proteins. Discovered decades ago, methodological limitations hindered progress at the time. Ring flips have gained new interest and experimentalists can measure the flip rate and thermodynamic quantities associated with it. LÄS MER

3. 2. Peptide fragment screening towards a new inhibitor of neutrophil elastase

   Master-uppsats, Lunds universitet/Livsmedelsteknik och nutrition (master)

   Författare :Tomas Szakacs; [2019]
   Nyckelord :pharmaceutical technology; läkemedelsteknologi; Chemistry; Technology and Engineering;

   Sammanfattning : The main purpose of this master thesis was to test a novel approach of finding leads for new pharmaceuticals, by using Solid Phase Peptide Synthesis (SPPS) in combination with Weak Affinity Chromatography (WAC). Put in a more concrete way, the objective was to find a lead for a better human neutrophil elastase inhibitor. LÄS MER

4. 3. Kinetic studies of carrier conjugated protease inhibitors

   Master-uppsats, Uppsala universitet/Institutionen för biologisk grundutbildning; Uppsala universitet/Institutionen för kemi - BMC

   Författare :Enrique Argenis López Olvera; [2019]
   Nyckelord :Proteases inhibitors; bioconjugates; enzyme kinetics; inhibition;

   Sammanfattning : Conjugates of soybean trypsin inhibitor (SBTI) and potato serine protease inhibitor (PSPI) immobilized on metal oxide particles of ~100nm diameter were prepared. Inhibition of trypsin hydrolysis of BAPA by these conjugates was measured and enzyme kinetics constants kcat, KM, kcat/KM and ki were determined. LÄS MER

5. 4. Characterisation of free and conjugated protease inhibitors from Solanum tuberosum

   Uppsats för yrkesexamina på avancerad nivå, Uppsala universitet/Institutionen för kemi - BMC

   Författare :Kristoffer Lundmark; [2017]
   Nyckelord :enzyme; trypsin; chymotrypsin; pancrease protease; serine protease inhibitors; SPI; potato tubers; potato; Solanum tuberosum; immobilized; aluminium oxide membranes; inhibitor-enzyme interaction;

   Sammanfattning : The main purpose of the master thesis project is to investigate the influence of selected serine protease inhibitors (SPI) on the catalytic action of the serine proteases chymotrypsin and trypsin, in a conjugated and non-conjugated state. The inhibitors included for this study were extracted from Solanum tuberosum, i.e.common potato. LÄS MER

7. 5. An investigation of protective formulations containing enzyme inhibitors : Model experiments of trypsin

   Uppsats för yrkesexamina på avancerad nivå, Institutionen för kemi - BMC

   Författare :Erika Billinger; [2012]
   Nyckelord :Trypsin; immobilized; dermatitis; NHS-agarose; inhibitor; protective formulations; enzyme inhibitor; active barrier; NHS-activated Sepharose;

   Sammanfattning : This master thesis considers an investigation of protective formulations (ointment, cream) containing enzyme inhibitors. Model experiments have been made on the enzyme trypsin. It is well accepted that feces and urine are an important causing factor for skin irritation (dermatitis) while using diaper. LÄS MER